This federal Project Grant award, identified as F31NS137765, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $173,140 grant, awarded on Sep 30, 2024, supports research to investigate the role of neural activity in the degeneration of midbrain dopamine neurons, which is a key pathological process in Parkinson's disease. The project will utilize...
This Project Grant award of $527,037 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award supports research at New York University (NYU) to investigate how the basal ganglia and motor thalamus in the human brain integrate cognitive and motor processes, with the goal of developing brain stimulation strategies to treat movement and...
This federal Project Grant award of $476,643.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), supports research to study the neurophysiological basis of impaired gait in mouse models of Parkinson's disease. The key objectives are to examine how the dorsolateral striatum and substantia nigra pars reticulata, which are part of the basal ganglia, encode gait...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA program 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders, provides $1,087,733 to the University of Pittsburgh to conduct research on the role of dopamine signaling in valence-dependent learning. The research aims to: 1) measure dopamine's spatially segregated functions in valence-dependent associative learning, 2) identify the valence-specific...
This federal Project Grant award of $2,208,982 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to investigate the role of the interleukin-13 receptor in Parkinson's disease. The research aims to determine the molecular and cellular mechanisms by which activation of the interleukin-13 receptor alpha 1 (IL-13RA1) can affect the survival of dopaminergic...
This Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the basal ganglia network neurophysiology of depression in Parkinson's disease (PD). The objective is to identify basal ganglia neural activity associated with depression in PD, determine the brain regions and networks involved, and determine brain...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $350,036 to the University of Alabama at Birmingham (UAB) to investigate the cellular and molecular changes in specific striatal neurons that may underlie the development of levodopa-induced dyskinesia (LID), a debilitating side effect of Parkinson's disease medication. The...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $176,079 to Vanderbilt University Medical Center (VUMC) to characterize the neurophysiology of reward signaling in the subthalamic nucleus and dorsolateral prefrontal cortex, and determine how acute and chronic deep brain stimulation of the subthalamic nucleus impacts reward...
This federal Project Grant award, with the ID R01NS140256, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $1,227,794 award to Washington University in Missouri aims to advance the understanding of Parkinson's disease (PD) pathophysiology through precision mapping of the somato-cognitive action network (SCAN) and its connections to subcortical...
The federal Project Grant award R01NS139424, valued at $650,878.00, was awarded on September 16, 2024 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to understand the functional neuroanatomy of motor adaptation and skill learning processes, with a focus on the role of the posterior parietal cortex. Key products and services to be...