This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research to identify electrophysiological mechanisms of freezing of gait (FOG) in Parkinson's disease. The $578,329 award to the University of California, Los Angeles will leverage invasive brain recordings and immersive virtual reality to characterize neural activity in the...
This federal Project Grant award, identified as F31NS137765, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $173,140 grant, awarded on Sep 30, 2024, supports research to investigate the role of neural activity in the degeneration of midbrain dopamine neurons, which is a key pathological process in Parkinson's disease. The project will utilize...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,058,260 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Regents of the University of Minnesota. The grant will fund research to investigate the neurophysiology of movement transitions in Parkinson's disease with freezing of gait. The project aims to gain insight into the mechanisms and neurological biomarkers of freezing of gait, which could...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $350,036 to the University of Alabama at Birmingham (UAB) to investigate the cellular and molecular changes in specific striatal neurons that may underlie the development of levodopa-induced dyskinesia (LID), a debilitating side effect of Parkinson's disease medication. The...
This federal Project Grant award, totaling $481,049.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program. The project, titled "Substantia Nigra Circuits in Instrumental Action," aims to characterize how the substantia nigra pars reticulata (SNR) regulates divergent nigrostriatal dopamine pathways and determine the roles of specific...
This Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the basal ganglia network neurophysiology of depression in Parkinson's disease (PD). The objective is to identify basal ganglia neural activity associated with depression in PD, determine the brain regions and networks involved, and determine brain...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $469,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Michigan Technological University. The grant, titled "Dissecting Neural Circuit Mechanisms Underlying Pallidal Deep Brain Stimulation," will fund research to identify the neural elements and circuits necessary for the therapeutic effects of deep brain stimulation (DBS) of the globus...
This Project Grant award of $616,200.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders, will support research to explore the role of neuromelanin accumulation in dopamine neurons and its impact on Parkinson's disease. The primary awardee, the Oklahoma Medical Research Foundation (OMRF), will leverage expertise across three established labs to investigate the...
This Project Grant award from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), is funding a research project to investigate the neural mechanisms underlying cognitive contributions to walking as an early marker for risk of Alzheimer's disease and related dementias (ADRD). The total award amount is $2,030,488 and the project period runs from Sep 17, 2024 to May 31, 2029. The research aims to: 1) Investigate gait deficits during tasks requiring...
This federal Project Grant award, with the ID R01NS140256, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $1,227,794 award to Washington University in Missouri aims to advance the understanding of Parkinson's disease (PD) pathophysiology through precision mapping of the somato-cognitive action network (SCAN) and its connections to subcortical...