The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $176,079 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Vanderbilt University Medical Center (VUMC) on January 1, 2025. The 5-year grant funds research by principal investigator Dr. Sarah Bick to characterize the neurophysiology of reward signaling in the subthalamic nucleus and dorsolateral prefrontal cortex of Parkinson's disease patients. The project aims to 1) define the neurophysiological correlates of reward signaling, 2) determine the impact of acute subthalamic nucleus stimulation on reward signaling, and 3) assess how chronic subthalamic nucleus stimulation alters reward signaling. The long-term goal is to develop improved neuromodulation strategies for cognitive and psychiatric symptoms associated with Parkinson's disease.
Generated 1/28/25, 7:58 AM