Project Grant R01NS137020

Award Date 9/15/24
Completion Date 8/31/29
Dollars Obligated $403K
Federal Grant Program
93.372
Assistance Type
Project Grant
Place of Performance
Dallas, TX 75390, USA
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The key objectives of this research project are to: 1) identify the in vivo connectome architecture of the hippocampal network and how it regulates neural activity patterns; 2) measure how in vivo activity patterns across this network change synaptic weights; and 3) establish how those synaptic changes impact overall circuit function. The work will utilize a combination of large-scale in vivo electrophysiology, computational analysis, and optical labeling of active neural populations to provide fundamental insights into the principles underlying dynamic information processing and storage within the hippocampal network. This research is being conducted by the University of Texas Southwestern Medical Center.

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