The National Institute of Mental Health (NIMH) awarded a 5-year, $781,119 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The Regents of the University of California, San Francisco (UCSF). The grant will fund research to "dissect the circuits and population dynamics that represent unconditioned and conditioned stimuli in the ventral hippocampus." The project aims to leverage anatomical targeting, large-scale population recording, computational tools, and cell-type specific manipulation to understand how ventral CA1 neurons in the hippocampus acquire, update, and store information during associative learning. The findings could provide insights into the circuit mechanisms contributing to cognitive and emotional disorders with underlying dysfunction in associative learning processes.
Generated 3/18/25, 3:30 AM