The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Trustees of Columbia University in the City of New York, doing business as the Health Sciences Division, a $2,554,313 federal Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant, which runs from Sep 1, 2023 to Aug 31, 2026, will support research to determine if targeted in vivo manipulations of local circuit control...
The University of Chicago received a $3.89 million Project Grant from the National Institutes of Health National Institute of Neurological Disorders and Stroke under the 21st Century Cures Act Brain Research through Advancing Innovative Neurotechnologies program. The grant will fund research from August 2022 through August 2025 to directly measure and manipulate the spiking activity of locus coeruleus and ventral tegmental area axons in the hippocampus of mice during hippocampal-dependent...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), will support the development of a novel set of methodologies for simultaneous, distributed perturbation of multiple cortical regions using patterned light. The primary objective is to infer how large-scale patterns of cortical activity underlie decision-making behaviors...
The Regents of the University of Michigan was awarded a $646,000 project grant from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The funding will support research to identify the neural processes within the paraventricular nucleus of the thalamus (PVT) that underlie individual variation in cue-motivated behavior. Using fluorescence-based...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $234,000.00 to investigate how inhibitory synapses in the brain regulate the structure and function of excitatory synapses throughout brain development. The research aims to elucidate the cellular and synaptic mechanisms by which inhibitory GABAergic synapses heterosynaptically modulate excitatory glutamatergic synapse formation and elimination....
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, is providing $290,688 to Brandeis University to conduct research on the role of primary cilia signaling in regulating the excitation-inhibition balance in the mature brain. The research aims to determine the source of somatostatin release that modulates synaptic properties...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is supporting research to investigate the functional logic of local circuits in auditory and parietal cortices. The $594,286 award to the University of Pittsburgh, with a project period from August 2024 to July 2029, will compare the spatial and functional properties of excitatory...
The Johns Hopkins University received a $1,490,248 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The award supports a 3-year research project titled "Cortical Circuit Dynamics Underlying Multisensory Decision Making." The project aims to investigate how the brain integrates visual, vestibular, and kinesthetic...
This $1,380,070 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research by Duke University to advance the understanding of human neural circuit design, with a focus on cortical interneurons. The 3-year project will leverage live human brain specimens and novel genetic tools to generate a multimodal phenotypic catalog of human interneurons and characterize their functional organization within neural...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,836,071 Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to the University of Chicago. This 3-year grant will fund research to parameterize the relationship between motor cortical reactivation during sleep and motor skill acquisition in freely behaving marmoset monkeys. The project aims to develop a more nuanced model of...