Project Grant R01MH139889
- The National Institute of Mental Health (NIMH) awarded a $449,958 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Virtuallybetter Health LLC on Sep 12, 2025. The grant aims to improve adherence and clinical outcomes in evidence-based treatment for obsessive-compulsive disorder (OCD) through the development of OC-GO, a novel interactive digital health tool. OC-GO is designed to enhance patient adherence to exposure and response prevention (ERP) treatment by...
- The University of Southern California (USC) was awarded a $1,330,840 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The grant, titled "MEGA-OCD: A Global Data-Driven Initiative to Discover Biosignatures of OCD," will establish biosignatures of obsessive-compulsive disorder (OCD) by combining multimodal neuroimaging data from two international OCD consortia. This highly-powered global study aims to...
- The National Institute of Mental Health (NIMH) awarded a $514,178 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the Laureate Institute For Brain Research, LLC in Oklahoma City, Oklahoma. The grant will support research to better understand the mechanistic relationship between brain circuit function and abnormalities in negative valence system behaviors, such as anhedonia and rumination, that contribute to treatment-resistant depression. The project will employ...
- The National Institute of Mental Health (NIMH) awarded a $282,625 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of Virginia. The project aims to develop a non-invasive strategy to degrade perineuronal nets (PNNs) in the brain as a novel therapeutic approach for treating excessive repetitive behavior, a common feature of conditions like obsessive-compulsive disorder and autism. The grant will fund the use of magnetic resonance-guided,...
- This Project Grant award is funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The $194,899 award supports a 5-year research project titled "Dissecting Neurocognitive Components of Compulsivity Using Computational Modeling and EEG" at the Icahn School of Medicine at Mount Sinai. The project aims to advance understanding of the neurocognitive mechanisms underlying compulsivity, which is a transdiagnostic maladaptive...
- This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 - Mental Health Research Grants provides $638,872 to The Feinstein Institutes for Medical Research to conduct research on "Elucidating Reward Network Modulation in Medial Forebrain Bundle Deep Brain Stimulation for Treatment Resistant Depression". The goal is to use brain imaging to understand how deep brain stimulation of the medial forebrain bundle impacts the brain's reward processing...
- This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is for a total of $420,519 over a 2-year period from May 15, 2025 to May 14, 2027. The grant supports research to explore the use of temporal interference (TI) electrical neurostimulation as a non-invasive method for deep brain stimulation. The research objectives are to: 1) characterize the effects of TI on brain activity and functional...
- The National Institute of Mental Health (NIMH) awarded a $792,441 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The Mclean Hospital Corporation in Belmont, MA. The grant, awarded on April 15, 2025, will support a research project titled "Tracking the Dynamic Trajectory of Behavioral, Physiological, and Neurobiological Stress Responses in Female Adolescents at High and Low Familial Risk for Depression." The project aims to investigate how parental...
- The National Institute of Mental Health (NIMH) awarded a $1,199,261 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Ampa Inc. The grant, awarded on September 15, 2025, will fund the development of a next-generation Transcranial Magnetic Stimulation (TMS) system that aims to make highly effective, personalized depression treatment more accessible and scalable. The key innovations include precision TMS targeting using neurocardiac response signals, camera-based...
- This federal Project Grant award for $633,438, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to develop a data-driven framework for real-time neural control using patterned microstimulation. The research aims to investigate the principles governing multi-electrode microstimulation in the primate prefrontal cortex, and introduce a novel data-driven algorithm to predict optimal stimulation patterns. The...
The National Institute of Mental Health (NIMH) awarded a $778,543 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Baylor College of Medicine. The grant, which runs from August 1, 2025 to July 31, 2030, supports research on the "Neurophysiological Investigation of the Approach-Avoidance Axis in OCD: Applications to Neuromodulation". The research aims to develop a mechanistic understanding of how deep brain stimulation (DBS) therapy can be used to treat obsessive-compulsive disorder (OCD) by investigating the relationship between clinical symptoms, behavioral patterns, and neural activity. The goal is to advance the scientific understanding of DBS for OCD and explore how it can help patients overcome their pathological fear-based avoidance behaviors.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $778.5k | 7/25/25 |