This Project Grant award, with federal grant ID R01NS138733, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The $378,453 award will fund a 3-year research project focused on advancing the understanding of temporal interference (TI), an innovative non-invasive brain stimulation technique. The key products or services to be delivered under...
This federal Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), will support the development of a causal wiring diagram of transdiagnostic brain functions. The $781,464 award, effective July 1, 2024 through February 28, 2029, will enable researchers at Brigham & Women's Hospital Inc. to use brain stimulation technology and resting-state functional MRI to map the causal circuitry connected to brain...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA Program 93.242 - Mental Health Research Grants is focused on elucidating the mechanism of action for medial forebrain bundle deep brain stimulation (MFB DBS) in treating treatment-resistant depression (TRD). The overall objective is to identify metabolic and functional imaging changes in the reward network induced by therapeutic MFB DBS that may serve as biomarkers for modulation of reward...
The National Institute of Mental Health (NIMH) awarded a $498,429 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the Children's Research Institute in Washington, D.C. The project, titled "Identifying the Multi-Modal Factors that Determine Individual Response to tDCS," aims to apply advanced machine learning algorithms to a unique multimodal dataset of over 225 transcranial direct current stimulation (tDCS) sessions. The goal is to determine which factors, such as...
The National Institute of Mental Health (NIMH) awarded a $147,656 Project Grant (CFDA 93.242 - Mental Health Research Grants) to Beth Israel Deaconess Medical Center, Inc. in Boston, MA. The grant, with an award date of December 3, 2024 and ultimate completion date of June 9, 2026, will fund a study to develop a data-driven framework for mapping the effects of transcranial electrical stimulation on audiovisual integration and hallucinations. The research aims to determine if cathodal...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research to optimize methods for measuring brain excitability in depression. The $784,096 award to The Leland Stanford Junior University will investigate how adjusting transcranial magnetic stimulation (TMS) parameters affects neural activity, optimize a targeting system to enhance short-latency TMS-evoked potentials, and test how these...
The National Institute of Mental Health (NIMH) awarded a $505,311 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Intelligent Imaging Innovations, Inc. (3i) to develop a commercial instrument for large-scale, all-optical electrophysiology. The project aims to combine advanced optical techniques, including volumetric neural activity imaging and computer-generated holography, to enable simultaneous optical recording and manipulation of neuron activity across multiple...
This $160,272 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports a research project titled "Theta Burst Modulation of Hippocampal-Cortical Rhythms in Schizophrenia." The overarching goal is to investigate whether connectivity-guided theta burst stimulation (TBS) can alter hippocampal neural activity and cognitive function in patients with schizophrenia. The project will involve a combination...
This U01 Cooperative Agreement award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $2,090,280 to support a research project titled "Use of Alpha-Frequency Deep Transcranial Interference Stimulation (TIS) to Understand and Modify Temporal Dynamics of Face Emotion Recognition and Social/Affective Function." The primary research objectives are to evaluate the effects of TIS, a non-invasive brain stimulation...
This Project Grant award from the National Institute of Mental Health (NIMH), under CFDA Program 93.242 Mental Health Research Grants, provides $417,200.00 in funding to Emory University to characterize and manipulate large-scale neural activity patterns in the brain. The key objectives are to: 1) Use simultaneous wide-field optical imaging and functional MRI to determine if patterns of quasi-periodic brain activity observed in fMRI reflect underlying neural dynamics, and 2) Assess whether...