Project Grant R42MH142197
- The National Institute of Mental Health (NIMH) awarded a $778,543 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Baylor College of Medicine. The grant, which runs from August 1, 2025 to July 31, 2030, supports research on the "Neurophysiological Investigation of the Approach-Avoidance Axis in OCD: Applications to Neuromodulation". The research aims to develop a mechanistic understanding of how deep brain stimulation (DBS) therapy can be used to treat...
- The National Institutes of Health (NIH) awarded a $128,505 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to Rogers Memorial Hospital Inc. to conduct research on treating obsessive-compulsive disorder (OCD) in perinatal women. The project aims to leverage patient data from a large behavioral healthcare system to investigate the efficacy, safety, and tolerability of first-line OCD treatments, such as exposure and response prevention (ERP) and serotonin reuptake...
- The National Institute of Mental Health (NIMH) awarded a $282,625 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of Virginia. The project aims to develop a non-invasive strategy to degrade perineuronal nets (PNNs) in the brain as a novel therapeutic approach for treating excessive repetitive behavior, a common feature of conditions like obsessive-compulsive disorder and autism. The grant will fund the use of magnetic resonance-guided,...
- This Project Grant award is funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The $194,899 award supports a 5-year research project titled "Dissecting Neurocognitive Components of Compulsivity Using Computational Modeling and EEG" at the Icahn School of Medicine at Mount Sinai. The project aims to advance understanding of the neurocognitive mechanisms underlying compulsivity, which is a transdiagnostic maladaptive...
- The National Institute of Mental Health (NIMH) awarded a $1,444,181 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Colliga Apps Corp. in Austin, TX. The funding supports the development of a centralized platform that enables the fast and inexpensive creation, testing, and dissemination of expert-developed, evidence-based, AI-enhanced digital mental health therapies. This platform, called Colliga, aims to address key barriers to widespread adoption of digital...
- The National Institute of Mental Health (NIMH) awarded a $1,682,938 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The Washington University. The goal of this 5-year project is to optimize an automated chatbot program to provide efficient, scalable treatment for eating disorders (EDs). The project will build on prior research and use a multi-phase optimization strategy (MOST) to test four candidate ED treatment components targeting mechanisms like weight/shape...
- The National Institute of Mental Health (NIMH) awarded Bend Health, Inc. a $291,491 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to develop peer and caregiver support content for their existing Remote Rapid Crisis Support Team (RCST) intervention for adolescents with self-injurious thoughts or behaviors (SITBs). The project, titled "Progressing Bend Health's Digital Rapid Crisis Support for Adolescents and Caregivers," aims to create a more...
- The National Institute of Mental Health (NIMH) awarded a $1,174,487 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Georgia Tech Research Corporation to develop and pilot a naturalistic platform called the Holistic Realtime Measurement of Effort-Based Decision-Making (HORMES) system. This system will measure behavior and neural activity during an immersive virtual reality task that requires effortful physical locomotion. The project aims to characterize...
- The National Institute of Mental Health (NIMH) awarded a $499,887 project grant under the Mental Health Research Grants program (CFDA 93.242) to Docbotic Inc. in Naperville, IL. The grant funds the development of BETTERBOT, an SMS chatbot that integrates artificial intelligence and large language models to deliver evidence-based behavioral activation therapy tailored to individuals with traumatic brain injury (TBI). The project aims to address barriers to mental health care for TBI patients,...
- The National Institute of Mental Health (NIMH) awarded a $1,199,261 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Ampa Inc. The grant, awarded on September 15, 2025, will fund the development of a next-generation Transcranial Magnetic Stimulation (TMS) system that aims to make highly effective, personalized depression treatment more accessible and scalable. The key innovations include precision TMS targeting using neurocardiac response signals, camera-based...
The National Institute of Mental Health (NIMH) awarded a $449,958 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Virtuallybetter Health LLC on Sep 12, 2025. The grant aims to improve adherence and clinical outcomes in evidence-based treatment for obsessive-compulsive disorder (OCD) through the development of OC-GO, a novel interactive digital health tool. OC-GO is designed to enhance patient adherence to exposure and response prevention (ERP) treatment by providing real-time interactive guidance and support for patients between therapy sessions, as well as support for therapists to prioritize and track homework assignments. The project will conduct a Type I effectiveness-implementation randomized controlled trial to evaluate the impact of OC-GO on OCD treatment outcomes.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $450.0k | 9/10/25 |