Project Grant R01HD119124
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $688,436 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. The goal of this 5-year research project, starting on September 1, 2025, is to develop a novel matrix regenerative nanotherapeutic platform to treat early-stage pelvic organ prolapse (POP) in women....
- This federal Project Grant award of $1,321,600 from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) supports research to investigate the cellular mechanisms underlying recurrent vaginal prolapse in women after prolapse surgery. The research, to be conducted by The Leland Stanford Junior University from July 1, 2025 to June 30, 2027, aims to address the knowledge gap around altered tissue microenvironment and cellular function in the vaginas of women...
- This $123,156 Project Grant, awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a research study on the neurobiological underpinnings of chronic pelvic pain in adolescents. The key objectives are to: 1) examine personalized neural networks involved in gynecological chronic pelvic pain in adult females, 2) identify individualized trajectories of dysmenorrhea pathogenesis...
- This Project Grant award, valued at $643,049.00, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports the development of a physiomimetic model of endometrioma, a type of endometriotic lesion, to study processes driving lesion initiation, ovarian stroma invasion, and persistence in a chronic inflammatory environment. The research aims to uncover...
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- This federal Project Grant award of $205,000, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), is funding research to elucidate the role of serotonergic and purinergic signaling pathways in mediating nociception (pain sensation) within the female reproductive tract. The project, titled "Pain Mechanisms in the Female Reproductive Tract", aims to characterize these...
- This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), CFDA 93.865 Child Health and Human Development Extramural Research, provides $584,074 in funding to the University of Massachusetts Medical School (UMMS) to conduct research on the role of ion channels in uterine contraction, reproduction, and the uterine condition adenomyosis. The key goals are to investigate how the L-type calcium channels CaV1.2 and CaV1.3...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $595,864 Project Grant to the Magee-Womens Research Institute and Foundation in Pittsburgh, PA, effective August 15, 2025 and scheduled for completion on May 31, 2030. The grant, awarded under the NICHD's Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to elucidate the role of hyaluronan, a key extracellular matrix component, in the development...
- The federal Project Grant award, valued at $743,287.00 and funded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a multi-disciplinary research effort to uncover novel insights into endocervical mucus secretion. The primary goal of this 5-year project, which began on May 20, 2025, is to identify the cells and pathways that influence mucus changes in response to hormonal...
- This Project Grant award of $634,234 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) was provided to the University of Utah to conduct a cross-sectional observational study on the biomechanical adaptations of individuals with unilateral transhumeral amputations. The study aims to collect high-precision, 3D kinematic and morphological data on the shoulders of these patients to...
This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research, totals $634,331 and is effective from August 5, 2025 to July 31, 2030. The grant supports research by the University of Utah to identify early markers (precursor phenotypes) of pelvic organ prolapse (POP) through quantifying pelvic floor functional reserve. The goal is to advance prevention efforts for POP, a condition affecting up to 1 in 5 women who currently receive interventions only when they reach end-stage disease. The research will utilize MRI, clinical measures, and RNA sequencing of the levator ani muscle to understand structural, functional, and cellular/molecular domains of pelvic floor reserve and its decline over the lifespan, with the aim of developing screening and early detection methods to prevent advanced POP.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $634.3k | 8/4/25 |