Project Grant R01HD119910
- This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research, totals $634,331 and is effective from August 5, 2025 to July 31, 2030. The grant supports research by the University of Utah to identify early markers (precursor phenotypes) of pelvic organ prolapse (POP) through quantifying pelvic floor functional reserve. The goal is to advance prevention...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $595,864 Project Grant to the Magee-Womens Research Institute and Foundation in Pittsburgh, PA, effective August 15, 2025 and scheduled for completion on May 31, 2030. The grant, awarded under the NICHD's Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to elucidate the role of hyaluronan, a key extracellular matrix component, in the development...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $606,518 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Magee-Womens Research Institute and Foundation. The grant, awarded on June 5, 2025, supports research to develop and test the safety and feasibility of spermatogonial stem cell (SSC) transplantation and testicular tissue grafting techniques for restoring fertility in patients,...
- This Project Grant award, valued at $643,049.00, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports the development of a physiomimetic model of endometrioma, a type of endometriotic lesion, to study processes driving lesion initiation, ovarian stroma invasion, and persistence in a chronic inflammatory environment. The research aims to uncover...
- This federal Project Grant award of $1,321,600 from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) supports research to investigate the cellular mechanisms underlying recurrent vaginal prolapse in women after prolapse surgery. The research, to be conducted by The Leland Stanford Junior University from July 1, 2025 to June 30, 2027, aims to address the knowledge gap around altered tissue microenvironment and cellular function in the vaginas of women...
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- The U.S. National Institute of Child Health and Human Development (NICHD) awarded a $766,982 Project Grant to Carnegie Mellon University under the Child Health and Human Development Extramural Research program (CFDA 93.865). The project aims to develop and validate a novel computational framework to simulate uteroplacental hemodynamics and placentation, with the goal of identifying metrics for early detection of pregnancy complications related to abnormal placental formation. This research...
- This $123,156 Project Grant, awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a research study on the neurobiological underpinnings of chronic pelvic pain in adolescents. The key objectives are to: 1) examine personalized neural networks involved in gynecological chronic pelvic pain in adult females, 2) identify individualized trajectories of dysmenorrhea pathogenesis...
- The National Institute of Child Health and Human Development (NICHD) awarded a $2,045,782 Project Grant to Endomet Biosciences, Inc. on April 10, 2025 through the Child Health and Human Development Extramural Research program (CFDA 93.865). The funding aims to develop a novel, non-hormonal therapeutic for endometriosis, a prevalent and disabling disease for which no cure currently exists. The project seeks to advance the development of a compound called ENDO-205, which has demonstrated...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a $716,192 research project to investigate the early transcriptomic changes associated with the development of endometriotic lesions. The project, running from September 2025 to August 2030, will integrate single-cell, spatial, and bulk transcriptomics analyses of peritoneal...
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $688,436 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. The goal of this 5-year research project, starting on September 1, 2025, is to develop a novel matrix regenerative nanotherapeutic platform to treat early-stage pelvic organ prolapse (POP) in women. The research aims to slow POP progression by targeting pathways involved in elastic fiber breakdown, new fiber assembly, and tissue fibrosis using functionalized nanomaterial-drug complexes. This comprehensive approach seeks to restore extracellular matrix homeostasis and prevent or delay the worsening of POP, which currently has limited treatment options.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $688.4k | 8/25/25 |