Project Grant K08HD115842
- This $429,000 federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the gene and environmental influences on placental angiogenesis and severe fetal growth restriction. The University of Colorado-Denver, the awardee organization, will leverage induced pluripotent stem cell technology to better...
- This Project Grant award of $226,608.00 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) is funding research to identify the mechanistic link between fetal glucagon and placental nutrient delivery. The goal is to establish how fetal glucagon regulates placental lactogen secretion and uterine blood flow as an adaptive mechanism for matching nutrient supply to...
- This federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), is supporting research on the role of decidual extracellular vesicles in mediating placental insufficiency. The $654,671 award, which commenced on August 1, 2025 and is scheduled for completion by April 30, 2030, is being conducted by the awardee, Yale University. The key...
- The U.S. National Institute of Child Health and Human Development (NICHD) awarded a $766,982 Project Grant to Carnegie Mellon University under the Child Health and Human Development Extramural Research program (CFDA 93.865). The project aims to develop and validate a novel computational framework to simulate uteroplacental hemodynamics and placentation, with the goal of identifying metrics for early detection of pregnancy complications related to abnormal placental formation. This research...
- This $249,000 Project Grant was awarded by the National Institute of Child Health and Human Development (NICHD), a division of the U.S. Department of Health and Human Services, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research at the University of Florida focused on in utero interventions to prevent adverse metabolic health outcomes, including non-communicable diseases like cardiovascular disease, hypertension, and type 2...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $2,255,352 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Regents of the University of Colorado, doing business as the University of Colorado-Denver. The award, effective September 15, 2025 through May 31, 2028, will fund research to determine the cellular and molecular mechanisms involved in the transfer of inflammatory signals across...
- The federal Project Grant award of $429,000 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to characterize placental extracellular vesicles (EVs) throughout human pregnancy. The goal is to develop novel methods to image, count, isolate, and validate placental cell- and size-specific EVs from maternal blood, in order to monitor placental...
- This Project Grant award of $765,571 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research on placental fatty acid metabolism in gestational diabetes mellitus (GDM). The project aims to investigate sexual dimorphism in placental function and its role in adverse pregnancy outcomes associated with GDM, with a focus on understanding the effects of GDM...
- The National Institute of Child Health and Human Development (NICHD) awarded a $411,125 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Syracuse University to develop a microfluidic human placenta organoid model. The goal is to generate human trophoblast stem cells (HTSCs) from induced pluripotent stem cells and use them to create a placenta organoid system that can replicate early/mid-gestation placental development. The researchers will study the role of...
- The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and transition to independence as a physician-scientist in placental biology. The research project focuses on modeling the metabolic stress associated with FGR, analyzing the miRNA cargo within extravillous trophoblast-released extracellular vesicles, and determining if this cargo impairs trophoblast invasion and feto-placental endothelial angiogenesis. The project will be conducted at the University of Colorado-Denver.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $163.1k | 8/7/25 |