Project Grant R01HD114145
Award Date
8/1/24
Completion Date
5/31/29
Dollars Obligated
$456K
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Fort Collins, CO 80521, USA
Similar Awards
This federal Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) provides $127,959.00 to Colorado State University to study the connection between maternal obesity, gut microbiome, and cardiometabolic disease in women. The overarching goal is to test the hypothesis that maternal obesity and gut dysbiosis in preeclampsia leads to altered short-chain fatty acid signaling, contributing to fetal...
This $1,454,109 Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to understand the genetic and physiological mechanisms by which the placenta adapts to hypoxia (low oxygen) and the implications for fetal growth and development. The research aims to 1) characterize how individual placental cell type responses to hypoxia contribute to...
This Project Grant award, valued at $293,756 and funded by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research, aims to enhance understanding of placental dysfunction in common obstetric disorders. The primary awardee, the Institute for Systems Biology, will conduct integrated multi-omic analysis of placental samples to identify molecular mechanisms associated with conditions like preeclampsia, preterm...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the mechanism by which fetal glucagon regulates placental nutrient delivery and uterine blood flow. The $148,568 award, effective from February 1, 2025 to July 31, 2026, will be provided to the University of Colorado-Denver to conduct this research. The key objectives are to...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $234,000.00 to The Regents of the University of Colorado (University of Colorado-Denver) to conduct research on a novel NF-kB genetic variant associated with preeclampsia. The key research objectives are to: 1) Establish whether the NF-kB variant (rs230511) is associated with impaired spiral artery...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), provides $234,000.00 in funding to Oregon Health & Science University (OHSU) to conduct research on immunometabolic dysregulations in the offspring of obese mothers. The key objective is to investigate how increased inflammation in high-fat diet-fed pregnant female mice impacts early-life...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $1,829,617 to the University of California, San Diego (UCSD) for a project titled "STEM CELL-BASED MODELING OF PLACENTAL DEFECTS ASSOCIATED WITH EARLY-ONSET PREECLAMPSIA." The project aims to establish stem cell-based models for studying abnormal trophoblast differentiation and function...
This $502,710.55 federal Project Grant award was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research to identify the molecular mechanisms linking lactation to metabolism, with the goal of developing interventions to improve lactation outcomes in women with obesity and/or diabetes. The key objectives are to: 1) Establish the effect of maternal...
This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $191,965 to the University of Texas at Austin to conduct research on the molecular mechanisms underlying preeclampsia, a serious pregnancy disorder. The key objectives are to: Identify and validate key transcription factors that drive preeclampsia-specific gene expression programs using human trophoblast stem cells as a...
This Project Grant award of $632,110.00 from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Medical College of Wisconsin, Inc. aims to reduce the risk of chronic hypertension and improve vascular function following preeclampsia, a major public health issue associated with postpartum hypertension and cardiovascular disease. The project will investigate the mechanisms behind the increased cardiovascular...