Project Grant R01HD113717
Award Date
8/16/24
Completion Date
5/31/29
Dollars Obligated
$1.6M
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Kansas City, KS 66160, USA
Similar Awards
This $107,860 Project Grant, awarded by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to understand the functional role of fibroid subtype mutations in developing new targeted therapies for uterine fibroids. The research aims to 1) determine the functional roles of HMGA2 over-expression and MED12 mutation in uterine fibroids, 2) predict and test drug compounds to target...
This $681,337 Project Grant awarded by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to Northwestern University supports research to investigate the role of the STAT3 signaling pathway in the growth of uterine leiomyomas (fibroids). The research aims to determine the functional importance of the STAT3 pathway in fibroid growth, particularly in tumors driven by MED12 mutations, and explore the potential of STAT3 inhibition as a therapeutic approach. The grant involves...
This $2,121,229 federal Project Grant award, titled "Evaluating the Impact of Altered Gene Expression on Uterine Fibroid Risk in African Ancestry Populations," was issued by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award aims to leverage the expertise and infrastructure of Vanderbilt University Medical Center (VUMC) and partners in Nigeria to better understand the genetic and...
This Project Grant award of $2,344,039 from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) supports research to identify factors contributing to the racial disparity in the incidence of uterine fibroids between Black and white women. The lead awardee, the Fred Hutchinson Cancer Center, will partner with researchers at Brigham & Women's Hospital and Boston University to: Determine if established fibroid...
This $584,074 Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the roles of specific ion channel subunits (Cav1.2 and Cav1.3) in regulating uterine contractility and their relationship to embryo implantation and the development of adenomyosis, a uterine disease affecting millions of women. The research aims to 1) examine the...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $1,963,122 to the University of Missouri System to conduct fundamental research on the molecular mechanisms regulating uterine development. The research aims to improve understanding of genetic and epigenetic factors governing epithelial specification, differentiation, and morphogenesis in the...
This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $390,000 to Thomas Jefferson University to evaluate the use of contrast-enhanced ultrasound (CEUS) and subharmonic-aided pressure estimation (SHAPE) techniques for assessing uterine fibroids before and after uterine artery embolization (UAE) procedures. The goals are to develop CEUS and SHAPE as alternatives to...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research program) provides $2,163,115 in funding to The University of Texas Health Science Center at San Antonio to conduct research aimed at disentangling the genetic mechanisms of endometriosis severity using single-cell multi-omics approaches. The research project, scheduled to run from September 1, 2024 to May 31, 2029, will involve...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will provide $1,576,519.00 to the University of Kansas Medical Center Research Institute, Inc. over the period from August 7, 2024 to May 31, 2029. The award will fund research to investigate the importance of the METTL3 gene in the development and maintenance of the mammalian placenta. The...
This federal Project Grant award for $131,085 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research to gain a better understanding of the role of uterine natural killer (UNK) cells in the pathobiology of endometriosis. The primary objectives are to characterize the receptor repertoire and functional capacity of UNK cells in women with and without endometriosis,...