Project Grant R01GM160991
Award Date 7/21/26
Completion Date 3/31/31
Dollars Obligated $768K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Virginia, USA
Similar Awards
- The National Institute of General Medical Sciences awarded the University of Virginia $425,145 on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop integrated microscopy and image processing technologies for long-term three-dimensional fluorescence imaging of bacterial biofilm communities on and within living human epithelial tissues. The project will create imaging and tracking systems capable of measuring single-cell three-dimensional bacterial...
- The National Institute of General Medical Sciences awarded the University of Virginia $539,999 on August 1, 2026, through the Biomedical Research and Research Training program (CFDA 93.859) to expand and operate the Biomedical Data Science Innovation Lab as a national training program for early-career faculty and senior postdoctoral fellows in biomedical data science. The award funds a year-long, immersive mentorship and research development program structured around virtual "microlab"...
- The National Institute of General Medical Sciences awarded the University of Virginia $395,698 on February 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate how the structural complexity of stem cell niches enables stem cell function during development and homeostasis. The research examines how niche structure and spatial organization coordinate the timing, intensity, and duration of signaling that controls stem cell activity. The work uses the C....
- The National Institute of General Medical Sciences awarded the University of Virginia $415,171 on March 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to design and develop cell-instructive viscoelastic hydrogels for three-dimensional cell culture that enable spatiotemporal control of mechanical properties and stress relaxation to model heterogeneous tissue mechanics during development, disease, and wound repair. The project comprises two themes. Theme 1...
- The National Institute of General Medical Sciences awarded Virginia Polytechnic Institute & State University $410,605 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop accurate and efficient solvent models for molecular simulations with applications in structure-based drug design and biomolecular research. The project focuses on advancing water model development for atomic-level computational simulations, addressing accuracy and...
- The National Institute of General Medical Sciences awarded the University of Virginia $444,125 on July 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the molecular mechanisms underpinning the formation and function of multinucleated cell types, including foreign body giant cells, syncytiotrophoblasts, myofibers, and osteoclasts. The research employs induced pluripotent stem cell modeling to resolve the role of syncytin 1 in multinucleation...
- The National Institute of General Medical Sciences awarded the University of Virginia $444,125 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the molecular mechanisms of chromatin signaling during DNA repair. The research examines how chromatin-modifying enzymes reorganize chromatin structure in response to DNA damage and restore that structure following repair, using histone ADP-ribosylation signaling during DNA excision repair...
- The National Institute of General Medical Sciences awarded the University of Virginia $441,474 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate how ion channels orchestrate endolysosomal system functions in myeloid phagocytes. The research pursues three complementary directions: characterizing how M7VS (specialized TRPM7-containing vesicles) drive phagosome maturation and endolysosomal homeostasis; dissecting the dual channel-kinase...
- Federal Grant Award Summary The University of Virginia received a $2.16 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2029. This award supports fundamental biomedical research investigating the mechanisms regulating inflammatory fibroblasts in wound healing. The project addresses a critical gap in understanding immune-stromal crosstalk...
- The National Institute of General Medical Sciences awarded the University of Virginia $444,125 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to study mitochondrial stress signaling pathways mediated through communication with other organelles. The research program comprises two projects. The first investigates mitochondrial DNA release triggered by mtDNA damage and its trafficking through the endosomal pathway, which results in innate immune...