Project Grant R25GM166888
- The National Institute of General Medical Sciences awarded the University of Virginia $425,145 on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop integrated microscopy and image processing technologies for long-term three-dimensional fluorescence imaging of bacterial biofilm communities on and within living human epithelial tissues. The project will create imaging and tracking systems capable of measuring single-cell three-dimensional bacterial...
- The National Institute of General Medical Sciences awarded the University of Virginia $768,087 on July 21, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to study utility-value interventions designed to boost science motivation and biomedical research career pursuits among community college students and instructors. The project addresses persistence barriers for community college students—over 40% of all undergraduate enrollment occurs at community colleges, with...
- The National Institute of General Medical Sciences awarded the University of Virginia $444,125 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the molecular mechanisms of chromatin signaling during DNA repair. The research examines how chromatin-modifying enzymes reorganize chromatin structure in response to DNA damage and restore that structure following repair, using histone ADP-ribosylation signaling during DNA excision repair...
- The National Institute of General Medical Sciences awarded the Regents of the University of Michigan $378,252 on September 3, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop virtual educational resources and training models in data visualization for biomedical researchers. The award funds creation of two complementary educational offerings. The first will generate resources enabling researchers to conduct constructive critiques of existing data...
- The National Institute of General Medical Sciences awarded the University of Virginia $444,125 on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the mechanisms of genome integrity maintenance and break-induced replication at repetitive DNA sequences. The research focuses on elucidating how break-induced replication drives genome instability in repetitive DNA regions, particularly telomere maintenance through the alternative lengthening...
- The National Institute of General Medical Sciences awarded $1.092 million to the Rector & Visitors of the University of Virginia on March 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop an impedance-activated recognition, tracking, and sorting (IARTS) system for label-free, near-real-time identification and isolation of phenotypically plastic cells based on multiparametric biophysical metrics. The IARTS system integrates neural networks with...
- The National Institute of General Medical Sciences awarded the University of Virginia $444,125 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to study mitochondrial stress signaling pathways mediated through communication with other organelles. The research program comprises two projects. The first investigates mitochondrial DNA release triggered by mtDNA damage and its trafficking through the endosomal pathway, which results in innate immune...
- The National Institute of General Medical Sciences awarded the University of Virginia $444,125 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop Spatiotemporal Multiplexed Antigen Revealing Technology (SMART), a platform for multiplexed, longitudinal imaging of live cells in vivo. SMART addresses the limitation of current single-cell analytical methods—flow cytometry, histological staining, sequencing, and mass cytometry—which are destructive...
- The National Institute of General Medical Sciences awarded the University of Virginia $415,171 on March 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to design and develop cell-instructive viscoelastic hydrogels for three-dimensional cell culture that enable spatiotemporal control of mechanical properties and stress relaxation to model heterogeneous tissue mechanics during development, disease, and wound repair. The project comprises two themes. Theme 1...
- The National Institute of General Medical Sciences awarded the University of Virginia $1.708 million on July 15, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to define the paralipidome and establish how local lipid nano-environments around membrane proteins regulate their structure and physiology. The project, titled "Defining the Paralipidome: A New Frontier in Membrane Biology," will employ recent technical advances to directly probe the local...
The National Institute of General Medical Sciences awarded the University of Virginia $539,999 on August 1, 2026, through the Biomedical Research and Research Training program (CFDA 93.859) to expand and operate the Biomedical Data Science Innovation Lab as a national training program for early-career faculty and senior postdoctoral fellows in biomedical data science. The award funds a year-long, immersive mentorship and research development program structured around virtual "microlab" seminars for ideation and knowledge exchange, advanced mentorship training to equip experienced scientists as interdisciplinary guides, and a culminating five-day in-person intensive workshop where participant teams develop grant-ready research proposals aligned with emerging NIH priorities. Each program year focuses on a new high-impact biomedical theme, such as artificial intelligence for precision medicine or data-driven approaches in clinical neuroscience, selected in consultation with NIH program officers. The program is designed to build participants' technical, conceptual, and collaborative skills necessary to lead biomedical data science research. Performance occurs in Charlottesville, Virginia, with a period of performance from August 1, 2026, through March 31, 2031. The University of Virginia is the recipient and operator of the program.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $540.0k | 7/31/26 |