Project Grant R35GM161604
- Federal Grant Award Summary The University of Virginia received a $2.16M Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2029. This award supports fundamental biomedical research investigating the mechanisms regulating inflammatory fibroblasts in wound healing. The research addresses a critical knowledge gap concerning immune-stromal cell...
- Federal Grant Award Summary The University of Virginia received a $353,430 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 15, 2025, with completion targeted for July 31, 2029. The award supports investigator-initiated basic research examining the regulation of ceramide-1-phosphate (C1P) metabolism in cellular signaling networks and metabolic reprogramming. The...
- Federal Grant Award Summary The University of Virginia received a $400,530 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective June 1, 2025, through March 31, 2030. This award supports the development of advanced nanodisc technology platforms designed to investigate membrane protein-lipid interactions and their role in cellular signaling and physiology. The research will focus on...
- Federal Grant Award Summary Harvard College, through its Office for Sponsored Programs, received a $377,648 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded June 20, 2025, with completion targeted for December 31, 2026. The award supports fundamental research to identify the molecular and cellular mechanisms governing the formation of adult pluripotent stem cells (APSCs) during...
- Federal Grant Award Summary The University of Virginia received a $125,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025 through August 31, 2027. This K99 award funds fundamental research examining the evolution and mechanisms of pathogen avoidance behavior in hosts, with explicit focus on distinguishing between innate avoidance (avoidance without prior...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $741,544 to the University of Virginia under the Biological Sciences program (CFDA 47.074) effective August 1, 2025, through July 31, 2028. Led by Dr. Ahmad Jomaa at the University of Virginia in collaboration with Dr. Simone Mattei at the EMBL Imaging Center in Germany, this Project Grant supports fundamental research investigating ribosome tethering to mitochondria in...
- Federal Grant Award Summary The University of Massachusetts Medical School received a $460,625 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025 through August 31, 2030. This award supports fundamental research to advance understanding of gene regulatory networks (GRNs)—the molecular mechanisms that control cell identity, function, and responses to external stimuli in...
- Federal Grant Award Summary The University of Virginia received a $1.402 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2025 through June 30, 2030. The award supports the establishment and operation of the University of Virginia Medical Scientist Training Program (MSTP), which trains the next generation of biomedical scientists and physician-scientists through an...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) awarded a $380,540 Project Grant to the University of California, Irvine, effective September 1, 2025, through June 30, 2030. The award supports fundamental research investigating epigenetic regulation mechanisms in human embryonic stem cell (hESC) lineage specification. The research program will examine the relationship...
- Federal Project Grant Award Summary The University of Alabama at Birmingham received a $394,434 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025 through August 31, 2030. This award supports fundamental biomedical research investigating the epigenetic mechanisms that regulate cellular identity and developmental potential, specifically examining how epigenetic...
The University of Virginia received a $395,698 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective February 15, 2026 through January 31, 2031. The award supports fundamental research investigating how the structural complexity and spatial organization of stem cell niches enable precise regulation of stem cell function during development and tissue homeostasis. Using the C. elegans germ line as a model system, the research examines how niche structure coordinates the timing, intensity, and duration of signaling that controls stem cell quiescence, proliferation, and differentiation—processes critical to understanding basic stem cell biology and applicable across multiple tissue types and disease contexts. The research deliverables include scientific discoveries and publications advancing understanding of niche-mediated stem cell regulation through molecular and cellular characterization of niche components and their organizational principles. By employing C. elegans genetic tools and advanced four-dimensional in vivo imaging capabilities, the investigation will generate foundational knowledge applicable to stem cell regulation in developing embryos, adult tissues such as skin and intestine, and cancer biology. The outcomes are intended to close critical knowledge gaps regarding how niche structure facilitates stem cell control, with implications for improving human health outcomes in regenerative medicine and disease prevention.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $395.7k | 2/6/26 |