Project Grant R01EY037468
Award Date 9/1/25
Completion Date 4/30/30
Dollars Obligated $574K
Federal Agency
Awardee
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Cleveland, OH 44195, USA
Similar Awards
- This Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) is supporting research at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University to investigate the role of neuronal activity on retinal angiogenesis and blood-retina barrier (BRB) maturation. The $248,999 award, effective from May 1, 2025 to April 30, 2028, aims to elucidate how neuronal synaptic activity, specifically cholinergic and glutamatergic neurotransmitters,...
- This federal Project Grant award of $136,512.00 from the National Eye Institute's Vision Research program (CFDA 93.867) supports research conducted by The Children's Hospital Corporation (doing business as Boston Children's Hospital) in Massachusetts. The research project, titled "Transformations of Photic Information in Melanopsin Pathways," aims to investigate the mechanisms by which intrinsically photosensitive retinal ganglion cells (ipRGCs) convey photic information to the brain...
- This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides funding to researchers at the University of California, San Francisco (UCSF) to study the neural mechanisms underlying visual processing and behavior after photoreceptor degeneration. The $237,588 award, spanning June 2025 through December 2027, will leverage the vertical optokinetic reflex (OKR) - a visual behavior that tracks global motion - to investigate how cone degeneration disrupts noise...
- This $429,016 federal Project Grant awarded by the National Eye Institute (CFDA 93.867 - Vision Research) to Oakland University supports research to identify the mechanisms by which a subset of retinal amacrine cells, called starburst amacrine cells, initiate and propagate spontaneous cholinergic waves in the developing retina. The objectives are to determine the distribution and properties of these cholinergic wave "pacemaker" cells (Aim 1) and to elucidate the calcium-dependent...
- This Project Grant award from the National Eye Institute (NEI), part of the U.S. Department of Health and Human Services, provides $385,000.00 in funding to Wayne State University to conduct research on genetic and glial support mechanisms in acute and chronic models of photoreceptor degeneration. The research aims to understand, prevent, and treat vision-related conditions and diseases, a focus area of NEI's Vision Research federal grant program (CFDA 93.867). The study will compare...
- This federal Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) provides $144,362 to support research on the role of hyperglycemia and hyperinsulinemia in the breakdown of the blood-retinal barrier in diabetic retinopathy. The project aims to identify the spatial localization and functions of claudins, key tight junction proteins, in the retinal pigment epithelium (RPE) and test the hypothesis that regulation of RPE claudins by hyperglycemic...
- This federal Project Grant award of $143,569 was provided by the National Eye Institute (NEI), under its Vision Research program (CFDA 93.867), to the Rochester Institute of Technology (RIT) from July 1, 2025 to June 30, 2029. The goal of the research is to establish the molecular-level understanding of the phase diagram and liquid structure of concentrated eye lens protein mixtures, which is critical for addressing the leading cause of blindness worldwide - cataract disease. The research will...
- This $240,750 federal Project Grant award from the National Eye Institute's Vision Research program (CFDA 93.867) aims to investigate the role of neural-glial-vascular signaling in the development of the eye's vasculature. The research has two main objectives: 1) Characterizing vasculature development and how it is altered in mice with modified retinal waves, using quantitative approaches and live imaging, and 2) Establishing the maturation of the glial-vascular unit through immunofluorescence...
- The federal Project Grant award of $249,000.00 from the National Eye Institute (NEI) under the Vision Research grant program (CFDA 93.867) will support research at the University of Maryland, Baltimore (UMB) to elucidate unique spectral-temporal fluorescence signatures to determine stratification and redistribution of intracellular retinal pigment epithelial (RPE) cell pigment granules. The research aims to provide fundamental insight into the connection between retinal pigment redistribution...
- This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $475,442 to the University of California, Los Angeles (UCLA) to conduct research focused on understanding the mechanisms underlying the ingestion of photoreceptor outer segment tips by the retinal pigment epithelium (RPE). The research aims to investigate the dynamic actin polymerization and trogocytosis process involved in this essential cellular function, as well as the daily timing of outer...