Project Grant R01DK141516
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $765,701 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Boston, Massachusetts. The grant, titled "Mapping Mechanosensory Circuits from the Bladder to Barrington's Nucleus," will fund research to explore the neural circuits that encode bladder fullness and control urination. The project...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $176,201 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of California, Irvine. The grant, with an award date of July 15, 2025 and an ultimate completion date of March 31, 2030, will fund research to investigate the molecular changes in aging female urethral striated muscle and develop potential treatments for urethral dysfunction,...
- This federal Project Grant award of $690,451 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research on the role of bladder fibroblasts in regulating bladder function. The University of Pittsburgh will conduct studies to investigate the contractile properties of suburothelial fibroblasts and their contribution to the formation of bladder rugae, as well as the involvement of...
- This $2,557,146 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award was made to the Board of Regents of the Nevada System of Higher Education (UEI: WLDGTNCFFJZ3), operating through the University of Nevada, Reno, and will fund research to explore novel targets for gastrointestinal hormones and neuropeptides in the regulation of...
- This $647,290 federal Project Grant was awarded on July 1, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research conducted by the University of California, Los Angeles (UCLA) to study the interplay between brain oxytocin and CRF (corticotropin-releasing factor) systems in stress-related visceral analgesia versus hyperalgesia, and the...
- This federal Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $3,005,541.00 to Baylor College of Medicine to conduct research on the mechanisms driving age-dependent and sex-dependent changes in bladder immunity that contribute to recurrent urinary tract infections (UTIs) and other lower urinary tract disorders in older women. The...
- This federal Project Grant award of $726,140.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant aims to elucidate the neural circuits and cellular mechanisms underlying visceral pain processing in the spinal cord and brainstem, with the goal of advancing understanding and treatment of visceral pain conditions such as irritable bowel syndrome,...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $862,002 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Medical College of Wisconsin, Inc. The grant, awarded on March 1, 2025 with a completion date of February 28, 2030, will support an in-depth investigation of mechanisms for enhancing the motor function of fecal continence muscles to improve fecal incontinence in patients. The research aims...
- This $117,000 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to the Research Institute at Nationwide Children's Hospital. The project aims to define the mechanisms by which the transcription factor STAT3 contributes to antimicrobial host defense in the human urothelium (bladder lining) against urinary tract infections (UTIs). Key...
- This federal Project Grant award of $117,000 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) will support research on the role of substance P and its receptor MRGPRX2 in the pathophysiology of irritable bowel syndrome (IBS). The Regents of the University of Michigan, through its Office of Research and Sponsored Projects, will conduct the research project from June 2025 to May 2027. The...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $320,778 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Vermont & State Agricultural College. The project, titled "PACAP/PAC1R Signaling and CRH Intersections in Micturition Circuits: Effects of Stress and Injury/Inflammation," will investigate how changes in central micturition and peripheral sensory circuits due to stress and inflammation/injury may contribute to bladder pain syndrome and interstitial cystitis. The research aims to assess the role of pituitary adenylate cyclase activating polypeptide (PACAP)/PAC1 receptor signaling and corticotropin releasing hormone (CRH) interactions in these disorders. The award period is from Sep 15, 2025 to Aug 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $320.8k | 9/11/25 |