Project Grant R01DK142807
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $320,778 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Vermont & State Agricultural College. The project, titled "PACAP/PAC1R Signaling and CRH Intersections in Micturition Circuits: Effects of Stress and Injury/Inflammation," will investigate how changes in central micturition and peripheral sensory circuits due to...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through its Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $784,966 project grant to Brandeis University to investigate the sensory functions of pharyngeal enteric neurons in the nematode C. elegans. The 5-year project, starting on Sep 15, 2025 and ending on Jun 30, 2030, aims to study how enteric neurons detect and respond to internal chemical and mechanical cues, and how...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $176,201 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of California, Irvine. The grant, with an award date of July 15, 2025 and an ultimate completion date of March 31, 2030, will fund research to investigate the molecular changes in aging female urethral striated muscle and develop potential treatments for urethral dysfunction,...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $862,002 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Medical College of Wisconsin, Inc. The grant, awarded on March 1, 2025 with a completion date of February 28, 2030, will support an in-depth investigation of mechanisms for enhancing the motor function of fecal continence muscles to improve fecal incontinence in patients. The research aims...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $708,138 to support the development of a biomechanocompatible small molecule-releasing scaffold for bladder augmentation. The goal is to create an alternative to conventional surgical approaches that use detubularized bowel tissue, which can have significant complications. The...
- This federal Project Grant award of $690,451 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research on the role of bladder fibroblasts in regulating bladder function. The University of Pittsburgh will conduct studies to investigate the contractile properties of suburothelial fibroblasts and their contribution to the formation of bladder rugae, as well as the involvement of...
- This $769,097 Project Grant was awarded on September 5, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research conducted by the Pennington Biomedical Research Center in Baton Rouge, Louisiana to investigate a novel brain-to-pancreatic islet neural circuit that regulates glucose homeostasis. The research aims to establish the physiological...
- This federal Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $3,005,541.00 to Baylor College of Medicine to conduct research on the mechanisms driving age-dependent and sex-dependent changes in bladder immunity that contribute to recurrent urinary tract infections (UTIs) and other lower urinary tract disorders in older women. The...
- This $191,234 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research program) supports research to investigate the role of gastric dopaminergic signaling and its impact on gastrointestinal symptoms and levodopa pharmacokinetics in Parkinson's disease. The primary objectives are to examine dopamine signaling pathways in gastric mucosal biopsies of healthy controls and Parkinson's...
- This federal Project Grant award of $432,625 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The purpose of the grant is to create a dataset measuring urological function in 8 different rat strains at various life stages. This dataset, combined with previous data, will help researchers understand how urological function differs across rat strains and guide...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $765,701 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Boston, Massachusetts. The grant, titled "Mapping Mechanosensory Circuits from the Bladder to Barrington's Nucleus," will fund research to explore the neural circuits that encode bladder fullness and control urination. The project will use techniques like immediate early gene activity, RNA sequencing, fiber photometry, and calcium imaging to map how mechanical signals from the bladder are transmitted to the brain's pontine micturition control center. This research aims to provide a comprehensive understanding of how the brain senses and regulates the urinary system. The project period runs from September 2025 through May 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $765.7k | 9/2/25 |