Project Grant R01DK143049
- This $2,618,975 Project Grant was awarded on September 8, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports a 5-year research project led by the University of Texas Health Science Center at Houston to advance the development and functional capabilities of tissue-engineered intestine as a potential cure...
- This federal Project Grant award of $524,837 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is supporting research to investigate the role of enteric glial mechanotransduction and the impact of mechanical stress on postoperative ileus (POI) and postoperative gastrointestinal dysfunction (POGD). The research aims to better understand the pathogenic mechanisms of POI in...
- This federal Project Grant award of $726,140.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant aims to elucidate the neural circuits and cellular mechanisms underlying visceral pain processing in the spinal cord and brainstem, with the goal of advancing understanding and treatment of visceral pain conditions such as irritable bowel syndrome,...
- This federal Project Grant award of $117,000 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) will support research on the role of substance P and its receptor MRGPRX2 in the pathophysiology of irritable bowel syndrome (IBS). The Regents of the University of Michigan, through its Office of Research and Sponsored Projects, will conduct the research project from June 2025 to May 2027. The...
- The National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases awarded a $152,205 Project Grant to The Regents of the University of California San Francisco under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant funds research to investigate how vagal sensory neurons regulate autonomic responses to achieve metabolic homeostasis, and how downstream neuronal circuits in the nucleus tractus solitarius integrate...
- This $647,290 federal Project Grant was awarded on July 1, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research conducted by the University of California, Los Angeles (UCLA) to study the interplay between brain oxytocin and CRF (corticotropin-releasing factor) systems in stress-related visceral analgesia versus hyperalgesia, and the...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $320,778 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Vermont & State Agricultural College. The project, titled "PACAP/PAC1R Signaling and CRH Intersections in Micturition Circuits: Effects of Stress and Injury/Inflammation," will investigate how changes in central micturition and peripheral sensory circuits due to...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through its Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $784,966 project grant to Brandeis University to investigate the sensory functions of pharyngeal enteric neurons in the nematode C. elegans. The 5-year project, starting on Sep 15, 2025 and ending on Jun 30, 2030, aims to study how enteric neurons detect and respond to internal chemical and mechanical cues, and how...
- This Project Grant award, totaling $502,233, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research conducted by the Regents of the University of Michigan to investigate neuron populations in the nucleus of the solitary tract (NTS) that mediate the aversive and non-aversive suppression of food intake. The research aims to further...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $164,700 to the University of California, Davis to investigate the mechanosensitive regulation of intestinal smooth muscle cell calcium signaling during gut development. The overarching goal is to improve understanding of the underlying mechanisms contributing to prematurity-related...
This $2,557,146 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award was made to the Board of Regents of the Nevada System of Higher Education (UEI: WLDGTNCFFJZ3), operating through the University of Nevada, Reno, and will fund research to explore novel targets for gastrointestinal hormones and neuropeptides in the regulation of intestinal motility. The 4-year project aims to determine the localization of receptors for secretin, GLP-2, and CGRP in specific subtypes of interstitial cells of Cajal and PDGFRA+ cells, and characterize the actions of these peptides on calcium signaling and contractile behaviors in the small intestine and colon. The research will utilize cell-specific, transgenic manipulation and advanced imaging techniques to investigate the cellular mechanisms by which these peptides regulate gastrointestinal motility.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.6m | 9/15/25 |