This $320,053 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) supports a comprehensive research study on the mechanisms regulating skeletal connectivity in craniofacial development and disease. The research led by Dr. Amy Merrill at the University of Southern California aims to decode the molecular identities of craniofacial connective tissue cells, reveal their role in joint...
This federal Project Grant award, valued at $453,750.00 and issued by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program, supports research on the genetic mechanisms underlying a common craniofacial birth defect known as craniosynostosis. The award was granted to Trustees of Boston University, a prominent private research institution, to conduct a multi-year investigation into the role of the ERF gene in...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research Program (CFDA 93.121), aims to establish a novel zebrafish model to study the pathomechanisms underlying syndromic craniosynostosis, a common craniofacial birth defect. The $313,000 award to Emory University will fund a 2-year research project to comprehensively analyze the skeletal, cellular, and genetic changes in a unique zebrafish mutant...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $622,608 in funding to the Children's Hospital Medical Center in Cincinnati, Ohio to study the genomic and developmental mechanisms underlying frontonasal dysplasia, a congenital craniofacial disorder. The research aims to investigate how structural variations in the genome, particularly those affecting the regulatory...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will provide $306,600.00 to the Northern California Institute for Research and Education (NCIRE) over a 2-year period from September 2024 to September 2026. The funding will support research to elucidate the role of TGF-beta signaling in craniofacial fibrous dysplasia, a disabling skeletal disease. The project aims to...
This Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR), part of the Department of Health and Human Services, will fund research into the genetic basis of human skeletal facial morphology through July 2025. Provided under the Oral Diseases and Disorders Research program (CFDA 93.121), the $936,510 in funding will support two key aims. First, the awardee will enhance current mesh landmarking procedures for craniofacial bone by developing a dense quasi-landmark...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $452,681 Project Grant under the Oral Diseases and Disorders Research Program (CFDA 93.121) to The Regents of the University of California, San Francisco (UCSF). The grant supports research to understand the role of the ESCRT (Endosomal Sorting Complexes Required for Transport) machinery in regulating signaling pathways and lipid metabolism during mammalian craniofacial development. The research aims to characterize how...
This Project Grant award, with Federal Grant ID R35DE034348, was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121). The $2,055,996 award supports a research program to investigate skeletal stem cell plasticity as a central mechanism of craniofacial bone formation and disease. The research program aims to address fundamental mechanisms of craniofacial bone diseases from the...
This Project Grant award, with a total funding amount of $123,585, was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121). The award, with a start date of September 25, 2024, supports research to decipher the underlying mechanisms of craniofacial spliceosomopathies, rare genetic disorders affecting craniofacial and limb development. The principal investigator at New York University will...
This $619,304.36 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), supports research to understand the effects of transcription factor dosage on craniofacial morphology and disease. The research, led by the grantee Boston Children's Hospital, aims to develop tools to precisely modulate the dosage of key craniofacial transcription factors and assess the resulting molecular, cellular,...