Project Grant R01AG103428
- The National Institute on Deafness and Other Communication Disorders awarded Vanderbilt University Medical Center $136,911 on February 15, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to conduct a clinical trial feasibility study characterizing cognitive-linguistic and auditory processing profiles in adult cochlear implant recipients with poor speech recognition outcomes and to determine the feasibility of auditory and cognitive intervention...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $2,433,859 supports research at The Johns Hopkins University to investigate age-related hearing loss and cognitive decline. The key objectives are to study the molecular, cellular, and connectivity changes in the central auditory system during normal aging and Alzheimer's disease, with the goal of developing targeted therapeutic strategies. The research integrates single-cell sequencing,...
- The National Institute on Deafness and Other Communication Disorders, a component of the National Institutes of Health under the Department of Health and Human Services, awarded $350,000 to The Medical University of South Carolina on July 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate neural plasticity mechanisms in aging adults with hearing loss. The research targets two aspects of brain adaptation to age-related hearing loss:...
- The National Institute on Aging awarded Vanderbilt University Medical Center $707,033 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop and validate novel statistical machine learning approaches that leverage baseline neuroimaging data to increase the statistical power and cost-effectiveness of clinical trials in Alzheimer's disease and late-life depression. The project addresses the challenge of efficiently utilizing rich neuroimaging datasets collected at baseline...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded $435,875 to Vanderbilt University on May 15, 2026, under the Aging Research program (CFDA 93.866) to define characteristics of a resilient organelle interactome during aging. The research applies advanced 3D electron microscopy and artificial intelligence-based image analysis to map organelle interactions in Caenorhabditis elegans model organisms across the aging process. The work compares age-dependent...
- The National Institute on Aging awarded Vanderbilt University Medical Center $2,129,341 on August 15, 2026, under the Aging Research program (CFDA 93.866) to conduct multiscale functional assessment of white matter across the life span. The research investigates blood oxygenation level-dependent (BOLD) signals in white matter using functional magnetic resonance imaging (fMRI) to characterize how white matter function evolves across developmental, adult, and aging stages. The project quantifies...
- The National Institute on Deafness and Other Communication Disorders awarded Vanderbilt University Medical Center $158,696 on December 31, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to identify genetic biomarkers of central auditory structures that predict individual cochlear implant outcomes in adults with moderate to profound hearing loss. The fellowship research addresses the gap that 80 percent of variance in speech recognition outcomes...
- The National Institute on Aging awarded Vanderbilt University Medical Center $3,079,819 for a Project Grant (R01AG092663) on January 1, 2026, under the Aging Research program (CFDA 93.866). The award funds research probing mechanistic links between endothelial aging and dementia. The recipient will passage human induced pluripotent stem cells differentiated to endothelial cells (hiPSC-ECs) obtained from healthy adults and individuals with vascular contributions to cognitive impairment and...
- The National Institute on Deafness and Other Communication Disorders awarded the University of South Florida $164,329 on September 16, 2025, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to conduct parallel human and animal studies examining associations between extended high frequency hearing loss, speech-in-noise performance, and cognitive decline in aging populations. The funded research encompasses two coordinated aims. Aim 1 involves assessment...
- The National Institute on Aging awarded Vanderbilt University Medical Center $610,523 on September 1, 2026, under the Aging Research program (CFDA 93.866) to examine how declines in power wheelchair vendors have affected Medicare and Medicaid beneficiary access to equipment and mobility. The study uses national Medicare and Medicaid claims data, vendor ownership records, and home health assessments to describe changes in power wheelchair vendor availability and ownership between 2007 and 2024;...
The National Institute on Aging, part of the Department of Health and Human Services, awarded Vanderbilt University Medical Center $729,157 on September 4, 2026, under the Aging Research program (CFDA 93.866) to characterize age-specific communication and psychosocial outcomes in adults with cochlear implants across the adult lifespan. The project addresses a gap in understanding how age affects outcomes in cochlear implant recipients. Current clinical measures fail to capture the real-world lived experiences of implant users, and up to 42 percent of recipients report decisional regret, with older adults demonstrating poorer outcomes and higher decision regret. The research will execute three specific aims: characterizing age-related differences using a new core cochlear implant outcome set and auditory and cognitive tests with quantitative methods; identifying shared and unique communicative and psychosocial needs across age groups using qualitative approaches; and integrating quantitative and qualitative findings to identify age-specific outcome priorities. Work is performed in Forest Hills, Tennessee. The project period runs through May 31, 2031. This is a Project Grant, the standard assistance type for investigator-initiated research under the National Institute on Aging's broader mission to support biomedical and behavioral research on aging, with emphasis on Alzheimer's disease and related dementias.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $729.2k | 9/3/26 |