Project Grant R01DC022765
- Federal Project Grant Award Summary The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $464,646 Project Grant to Washington University on July 15, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The research project, titled "Cortical Mechanisms Underlying Hearing Deficits in Noisy Backgrounds After Noise Trauma," addresses noise-induced hearing loss (NIHL), a major public health problem affecting over...
- Project Grant Award Summary The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded The Medical University of South Carolina a Project Grant of $102,324 effective September 1, 2025, through August 31, 2027, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). This award supports research investigating macrophage and microglia dysfunction in age-related auditory nerve degeneration, with the objective of developing novel treatment...
- Federal Project Grant Summary The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded The Johns Hopkins University a Project Grant totaling $650,639 effective February 1, 2026 through January 31, 2031 to investigate crossmodal plasticity of adult corticothalamic circuits under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The research examines how visual deprivation triggers compensatory auditory system enhancements in adult mice...
- Federal Project Grant Award Summary The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a Project Grant totaling $410,534 to The Medical University of South Carolina (MUSC) on September 10, 2025, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). This research project, with a completion date of August 31, 2027, focuses on identifying genetic modifiers that influence hearing loss penetrance in the context of endothelin...
- Federal Grant Award Summary The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $484,738 Project Grant to the University of Miami's Office of Research Administration—School of Medicine on May 1, 2026 (CFDA 93.173: Research Related to Deafness and Communication Disorders) to develop an innovative bioengineered human pluripotent stem cell (hPSC) system for studying inner ear development and function. The research deliverables include: (1) design and validation of...
- Federal Project Grant Award Summary The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded The Johns Hopkins University a Project Grant of $194,270.00 on May 11, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to investigate the effects of early sensory loss on the developing auditory thalamocortical circuit. The research, conducted in Baltimore, Maryland through April 30, 2029, will establish foundational understanding...
- Federal Grant Award Summary The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded the University of Maryland, College Park a $585,000 Project Grant under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) on September 15, 2025, with a project completion date of August 31, 2028. The research investigates reinforcement mechanisms underlying auditory perceptual learning—the brain's ability to improve sound discrimination and detection...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $2,433,859 supports research at The Johns Hopkins University to investigate age-related hearing loss and cognitive decline. The key objectives are to study the molecular, cellular, and connectivity changes in the central auditory system during normal aging and Alzheimer's disease, with the goal of developing targeted therapeutic strategies. The research integrates single-cell sequencing,...
- Federal Grant Award Summary The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $244,740 Project Grant to the University of California, San Diego on September 30, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The project, titled "Multidimensional Analysis of Cochlear Pathology in Sensorineural Hearing Loss," will be performed through June 30, 2029, and focuses on developing artificial...
- Federal Project Grant Award Summary The Johns Hopkins University received a $582,552 Project Grant from the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), effective August 1, 2025 through July 31, 2028. This award funds research to understand auditory circuit organization and development following gene therapy treatment for congenital deafness caused by otoferlin variants. The...
The National Institute on Deafness and Other Communication Disorders awarded a $350,000 Project Grant to The Medical University of South Carolina on July 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support a five-year research initiative examining brain plasticity in aging adults with hearing loss through June 30, 2031. The project investigates how the aging brain adapts to age-related hearing loss (HL) by examining two key neuroplastic mechanisms: gamma-aminobutyric acid (GABA), the brain's primary inhibitory neurotransmitter, and adaptive myelination—the activity-dependent degeneration and enhancement of myelin that affects central nervous system function. The research aims to characterize how reduced GABA levels associated with hearing loss may increase cross-sensory plasticity, causing the aging brain to rely more heavily on multimodal (audiovisual) processing for speech recognition in noise. The deliverables include objective, non-invasive neuroimaging measurements to identify potential therapeutic candidates and quantify treatment outcomes, with research findings intended to inform future interventions using existing training approaches, neuromodulation techniques, and pharmaceutical treatments to enhance myelin and modulate GABA activity. The project prioritizes understanding the interaction between age and hearing loss on these neural mechanisms before therapeutic intervention, positioning the research to advance clinical rehabilitation success in this common chronic condition affecting aging populations.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $350.0k | 7/9/26 |