Project Grant R01AG100010
- The National Institute on Aging awarded Vanderbilt University Medical Center $2,129,341 on August 15, 2026, under the Aging Research program (CFDA 93.866) to conduct multiscale functional assessment of white matter across the life span. The research investigates blood oxygenation level-dependent (BOLD) signals in white matter using functional magnetic resonance imaging (fMRI) to characterize how white matter function evolves across developmental, adult, and aging stages. The project quantifies...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded Vanderbilt University Medical Center $729,157 on September 4, 2026, under the Aging Research program (CFDA 93.866) to characterize age-specific communication and psychosocial outcomes in adults with cochlear implants across the adult lifespan. The project addresses a gap in understanding how age affects outcomes in cochlear implant recipients. Current clinical measures fail to capture the real-world...
- The National Institute on Aging awarded Vanderbilt University Medical Center $3,079,819 for a Project Grant (R01AG092663) on January 1, 2026, under the Aging Research program (CFDA 93.866). The award funds research probing mechanistic links between endothelial aging and dementia. The recipient will passage human induced pluripotent stem cells differentiated to endothelial cells (hiPSC-ECs) obtained from healthy adults and individuals with vascular contributions to cognitive impairment and...
- The National Institute on Aging awarded Vanderbilt University Medical Center $707,033 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop and validate novel statistical machine learning approaches that leverage baseline neuroimaging data to increase the statistical power and cost-effectiveness of clinical trials in Alzheimer's disease and late-life depression. The project addresses the challenge of efficiently utilizing rich neuroimaging datasets collected at baseline...
- The National Institute on Aging awarded $735,047 to Vanderbilt University Medical Center on August 15, 2026, under the Aging Research program (CFDA 93.866) to conduct a randomized controlled trial testing a perioperative geriatric intervention for older adults undergoing major cancer surgery. The award funds a multicenter hybrid implementation-effectiveness trial enrolling 354 patients at two NCI-designated cancer centers. The intervention, called PERI-OP, consists of a preoperative in-person or...
- The National Institute on Aging awarded Vanderbilt University $423,142 on May 1, 2026, under the Aging Research program (CFDA 93.866) to develop esophageal stents integrating wireless soft actuators for restoring peristalsis in esophageal cancer. The project, designated R21AG095751, creates a novel esophageal stent equipped with magnetically actuated undulating sheets that mimic peristaltic motion to transport liquid and solid, addressing esophageal dysmotility in esophageal cancer and other...
- The National Institute on Aging awarded The University of Chicago $597,239 on September 1, 2026, under the Aging Research program (CFDA 93.866) to support investigation of inpatient rehabilitation facility (IRF) utilization and outcomes for older adult patients with and without Alzheimer's disease or other dementias (ADRD). The research examines comparative value and appropriateness of care delivery across post-acute care settings, specifically comparing higher-cost IRF care—which provides acute...
- The National Institute on Aging, a component of the Department of Health and Human Services, awarded Vanderbilt University Medical Center $669,660 on September 1, 2026, under the Aging Research program (CFDA 93.866) to investigate postsurgical pain and opioid use in older adults with mild cognitive impairment. The project will systematically evaluate the effects of mild cognitive impairment on pain processing, pain-relevant vagal inhibition, postsurgical pain experience, and opioid use...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded $435,875 to Vanderbilt University on May 15, 2026, under the Aging Research program (CFDA 93.866) to define characteristics of a resilient organelle interactome during aging. The research applies advanced 3D electron microscopy and artificial intelligence-based image analysis to map organelle interactions in Caenorhabditis elegans model organisms across the aging process. The work compares age-dependent...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded Weill Medical College of Cornell University $720,523 on June 15, 2026, under the Aging Research program (CFDA 93.866) to evaluate the impact of integrated dual-eligible special needs plans (D-SNPs) on utilization, quality, mortality, and chronic disease management among low-income individuals dually eligible for Medicare and Medicaid who qualify for Medicare based on disability. The study addresses a...
The National Institute on Aging awarded Vanderbilt University Medical Center $610,523 on September 1, 2026, under the Aging Research program (CFDA 93.866) to examine how declines in power wheelchair vendors have affected Medicare and Medicaid beneficiary access to equipment and mobility. The study uses national Medicare and Medicaid claims data, vendor ownership records, and home health assessments to describe changes in power wheelchair vendor availability and ownership between 2007 and 2024; assess whether reductions in vendor supply correlated with decreased power wheelchair use and repair utilization in Medicare; and evaluate whether declines in wheelchair use associated with reduced vendor availability produced disparate health impacts on dual-eligible beneficiaries navigating conflicting Medicare and Medicaid coverage rules. The research addresses documented vendor consolidation—the number of wheelchair vendors in traditional Medicare fell by more than half between 2013 and 2021—and associated beneficiary harms including extended wait times for wheelchair delivery and repairs, constrained mobility, delayed access to medical appointments, and increased risk of falls, pressure ulcers, and contractures. Performance occurs in Forest Hills, Tennessee, with a period of performance from September 1, 2026, through May 31, 2031. The award is classified as a Project Grant, a standard assistance type under the National Institute on Aging's mission to support biomedical and behavioral research directed toward understanding aging and age-related diseases and needs.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $610.5k | 8/14/26 |