Project Grant K99AG095149
- The National Institute on Aging awarded the Regents of the University of Michigan $654,999 on September 1, 2026, under the Aging Research program (CFDA 93.866) to assess cognitive functioning in the National Monitoring the Future (MTF) Panel Study. The award funds the addition of web-based cognitive measures to the MTF Panel, a nationally representative longitudinal study of high school seniors followed since 1975. The cognitive measures—assessing memory, numeracy, executive functioning, word...
- The National Institute on Aging awarded the Regents of the University of Michigan $284,108 on January 1, 2026, under the Aging Research program (CFDA 93.866) to investigate how mechanical changes in the aging brain affect microglial function and Alzheimer's disease progression. The project explores the relationship between age-related mechanical alterations in brain tissue—specifically decreased stiffness and increased viscoelasticity resulting from reduced tissue connectivity—and microglial...
- The National Institute on Aging awarded the Regents of the University of Michigan $758,442 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop and test two pragmatic interventions aimed at increasing brain donation among older adults at risk for Alzheimer's disease and related dementias. The project, "The Brain Gifting Counseling Program: A Novel Peer-Professional Intervention to Enhance Brain Donation Among Older Adults at Risk for Alzheimer's Disease and...
- The National Institute on Aging awarded Regents of the University of Michigan $2.114 million on September 2, 2026, under the Aging Research program (CFDA 93.866) to expand and enhance the National Neighborhood Data Archive (NANDA), a national repository of contextual measures designed for integration into aging research workflows and linkages with longitudinal studies. The award funds six specific aims. Three aims support NANDA's data infrastructure: administrative activities, data creation...
- The National Institute on Aging awarded the Regents of the University of Minnesota $1,291,486 on February 1, 2026, under the Aging Research program (CFDA 93.866) to investigate the relationship between childhood socioeconomic status and lead exposure and the risk of Alzheimer's disease and related dementias in late life. The project will create a novel research data source by linking participants in the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS; N=15,792) to their...
- The National Institute on Aging awarded Regents of the University of Michigan $131,760 on August 1, 2026, under the Aging Research program (CFDA 93.866) to support research on hippocampal-prefrontal interactions underlying trace memory in aging and a rodent model of Alzheimer's disease. The investigator will perform simultaneous electrophysiological recordings in the hippocampus and calcium imaging recordings in the prefrontal cortex of freely moving rats as they perform a trace conditioning...
- The National Institute on Aging awarded the Regents of the University of Michigan $1,703,843 on April 1, 2026, under the Aging Research program (CFDA 93.866) to generate prospective environmental chemical exposure data from stored biospecimens in the Health and Retirement Study cohort and examine associations between chemical and social exposures and Alzheimer's disease and related dementias (ADRD). The project performs state-of-the-art non-targeted analysis to measure chemical levels...
- The National Institute on Aging awarded Michigan State University (doing business as Henry Ford Health+Michigan State University Health Sciences) $624,029 on September 1, 2026, for research into dimensional complexity as a biomarker for cognitive resilience in aging and dementia under the Aging Research program (CFDA 93.866). The project will develop and clinically validate dimensional complexity (DC), a novel resting-state fMRI biomarker that quantifies dynamic brain activity organization, to...
- The National Institute on Aging awarded Michigan State University (doing business as Henry Ford Health+Michigan State University Health Sciences) $314,000 on April 1, 2026, under the Aging Research program (CFDA 93.866) to optimize and validate detection and modeling of the vascular and glymphatic systems in cerebral waste clearance using superparamagnetic iron oxide-enhanced susceptibility weighted imaging (SPIO-SWI), and to investigate cerebral waste clearance changes during Alzheimer's...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded the Regents of the University of Michigan $779,211 on September 2, 2026, under the Aging Research program (CFDA 93.866) to investigate the health, functional, and financial impacts of Medicaid disenrollment on adults ages 50-64 in Michigan. The research team will conduct a longitudinal two-wave survey of Michigan Medicaid enrollees ages 50-64 to evaluate how disenrollment affects insurance coverage,...
The National Institute on Aging awarded the Regents of the University of Michigan $116,079 on September 1, 2026, under the Aging Research program (CFDA 93.866) to assess how multilevel life course socioeconomic conditions relate to disparities in Alzheimer's disease and related dementias. The project examines socioeconomic trajectories at both individual and neighborhood levels in relation to cognitive decline, dementia incidence, and brain health indicators including structural magnetic resonance imaging and blood-based biomarkers in older adults. The research also assesses individual and neighborhood-level psychosocial resources—psychological resilience and neighborhood social cohesion—to identify potential intervention points. The applicant will use data from the Michigan Cognitive Aging Project, a regional community-based longitudinal cohort enriched for high Alzheimer's disease risk, and the Health and Retirement Study, a nationally representative longitudinal panel, linked with census-level neighborhood data from the National Neighborhood Data Archive. The award supports targeted training in assessing group differences in Alzheimer's disease risk and resilience using multilevel, life course methodological frameworks and expertise in functional neuroanatomy and biological markers. Work is performed in Ann Arbor, Michigan. The period of performance runs from September 1, 2026, through August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $116.1k | 8/4/26 |