Project Grant R01AG096229
- The National Institute on Aging awarded the Regents of the University of Michigan $116,079 on September 1, 2026, under the Aging Research program (CFDA 93.866) to assess how multilevel life course socioeconomic conditions relate to disparities in Alzheimer's disease and related dementias. The project examines socioeconomic trajectories at both individual and neighborhood levels in relation to cognitive decline, dementia incidence, and brain health indicators including structural magnetic...
- The National Institute on Aging awarded the Regents of the University of Michigan $758,442 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop and test two pragmatic interventions aimed at increasing brain donation among older adults at risk for Alzheimer's disease and related dementias. The project, "The Brain Gifting Counseling Program: A Novel Peer-Professional Intervention to Enhance Brain Donation Among Older Adults at Risk for Alzheimer's Disease and...
- The National Institute on Aging awarded the Regents of the University of Michigan $284,108 on January 1, 2026, under the Aging Research program (CFDA 93.866) to investigate how mechanical changes in the aging brain affect microglial function and Alzheimer's disease progression. The project explores the relationship between age-related mechanical alterations in brain tissue—specifically decreased stiffness and increased viscoelasticity resulting from reduced tissue connectivity—and microglial...
- The National Institute on Aging awarded Regents of the University of Michigan $131,760 on August 1, 2026, under the Aging Research program (CFDA 93.866) to support research on hippocampal-prefrontal interactions underlying trace memory in aging and a rodent model of Alzheimer's disease. The investigator will perform simultaneous electrophysiological recordings in the hippocampus and calcium imaging recordings in the prefrontal cortex of freely moving rats as they perform a trace conditioning...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded the Regents of the University of Michigan $779,211 on September 2, 2026, under the Aging Research program (CFDA 93.866) to investigate the health, functional, and financial impacts of Medicaid disenrollment on adults ages 50-64 in Michigan. The research team will conduct a longitudinal two-wave survey of Michigan Medicaid enrollees ages 50-64 to evaluate how disenrollment affects insurance coverage,...
- The National Institute on Aging awarded the Regents of the University of Michigan $1,703,843 on April 1, 2026, under the Aging Research program (CFDA 93.866) to generate prospective environmental chemical exposure data from stored biospecimens in the Health and Retirement Study cohort and examine associations between chemical and social exposures and Alzheimer's disease and related dementias (ADRD). The project performs state-of-the-art non-targeted analysis to measure chemical levels...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded $298,419 to the Regents of the University of Michigan on February 1, 2026, under the Aging Research program (CFDA 93.866, Assistance Listing Project Grant R01AG097771). The recipient will develop advanced statistical and computational methods for analyzing immune cell data to enhance understanding of the immune system's role in aging and age-related diseases. The project addresses analytical...
- The National Institute on Aging awarded Michigan State University (doing business as Henry Ford Health+Michigan State University Health Sciences) $314,000 on April 1, 2026, under the Aging Research program (CFDA 93.866) to optimize and validate detection and modeling of the vascular and glymphatic systems in cerebral waste clearance using superparamagnetic iron oxide-enhanced susceptibility weighted imaging (SPIO-SWI), and to investigate cerebral waste clearance changes during Alzheimer's...
- The National Institute on Aging awarded Michigan State University (doing business as Henry Ford Health+Michigan State University Health Sciences) $624,029 on September 1, 2026, for research into dimensional complexity as a biomarker for cognitive resilience in aging and dementia under the Aging Research program (CFDA 93.866). The project will develop and clinically validate dimensional complexity (DC), a novel resting-state fMRI biomarker that quantifies dynamic brain activity organization, to...
- The National Institute on Aging awarded the University of Memphis $146,000 on September 4, 2026, under the Aging Research program (CFDA 93.866) to investigate longitudinal patterns of multiple behavioral risk factors and their joint effects on cognitive aging. The recipient will analyze 24 years of data from the Health and Retirement Study, a nationally representative longitudinal survey of U.S. adults age 51 and older, linked with neighborhood contextual data, to examine how physical...
The National Institute on Aging awarded the Regents of the University of Michigan $654,999 on September 1, 2026, under the Aging Research program (CFDA 93.866) to assess cognitive functioning in the National Monitoring the Future (MTF) Panel Study. The award funds the addition of web-based cognitive measures to the MTF Panel, a nationally representative longitudinal study of high school seniors followed since 1975. The cognitive measures—assessing memory, numeracy, executive functioning, word knowledge, and fluid intelligence—will be administered as a Healthy Brains Module to approximately 9,600 eligible MTF panel participants who will reach ages 50, 55, 60, or 65 during 2026 and 2027. These measures were developed and previously used by the Health and Retirement Study and the Understanding America Study for online administration. The award examines how educational experiences and substance use from adolescence through adulthood associate with midlife cognitive function and risk for Alzheimer's disease and related dementias, building on the MTF Panel's existing dataset of approximately 120,000 respondents across 50 cohorts enrolled since 1976. Work is performed at Ann Arbor, Michigan, with a period of performance from September 1, 2026, through May 31, 2031. The funding is classified as a Project Grant under the National Institute on Aging's mission to support biomedical and behavioral research in aging with emphasis on preventing and treating Alzheimer's disease and related dementias.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $655.0k | 8/11/26 |