Project Grant HT94252310551

Summary The National Eye Institute awarded a $1.01M Vision Research grant (CFDA 93.867) to Washington University in St. Louis beginning July 1, 2025, through March 31, 2030. The project, titled "Visual Feature Competition Between Central and Peripheral Retinal Pathways," will deliver fundamental neuroscience research investigating how the retina processes competing visual signals that control eye fixation and the optokinetic reflex (OKR). The primary products include empirical findings...

Federal Grant Award Summary The National Eye Institute (NEI) awarded University of California, Irvine $179,964 under the Vision Research program (CFDA 93.867) on March 1, 2025, for a project grant extending through July 10, 2029. The project focuses on developing deep learning-based biomarkers for optic neuropathies using retinal Optical Coherence Tomography (OCT) imaging analysis. The research will employ advanced computational techniques, including deep generative models, neural field image...

Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $571,206 to the University of Maryland, Baltimore on May 1, 2026, to support research on the development, refinement, and validation of sensitive and robust adaptive optics-optical coherence tomography (AO-OCT) biomarkers for glaucoma detection and progression monitoring. The project will deliver two primary research products: (1) validated AO-OCT biomarkers through longitudinal...

Federal Project Grant Award Summary The National Eye Institute (NEI) awarded New York University School of Medicine a $673,747 Vision Research project grant (CFDA 93.867) commencing June 1, 2025, and concluding May 31, 2030, to develop advanced optical imaging technology for early detection of age-related macular degeneration (AMD). The research focuses on advancing visible-to-near-infrared spanning optical coherence tomography (OCT) to achieve half-micron axial resolution for retinal imaging,...

ADAPT Trial Cooperative Agreement Summary The National Eye Institute (NEI) awarded The Regents of the University of California, San Francisco a cooperative agreement valued at $1,662,447 (awarded May 1, 2026, with completion anticipated April 30, 2030) under the Vision Research program (CFDA 93.867) to conduct the Adalimumab Dose Adjustment for Pediatric Uveitis Treatment (ADAPT) Trial. This multicenter, randomized controlled trial will generate evidence-based dosing guidelines for adalimumab in...

Federal Grant Award Summary The National Eye Institute (NEI) awarded a $440,275 Project Grant to The Research Foundation for the State University of New York (RF SUNY) for research on ATOH7 interacting proteins involved in retinal ganglion cell (RGC) genesis. The two-year project, effective April 1, 2026 through March 31, 2028, is conducted under the Vision Research federal grant program (CFDA 93.867) and focuses on identifying and characterizing the protein factors that interact with ATOH7, a...

Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded a $534,000 Project Grant to Boston Children's Hospital for a two-year planning initiative (April 1, 2026 – March 31, 2028) focused on developing a treatment pathway for pediatric inherited retinal disorders (IRDs) amenable to antisense oligonucleotide (ASO) therapy. The project delivers three primary products: (1) streamlined genetic eligibility analysis protocols to identify...

The National Institute on Aging (NIA) awarded a $2,126,420 Project Grant (CFDA 93.866 - Aging Research) to The Trustees of the University of Pennsylvania to evaluate retinal imaging biomarkers that can distinguish frontotemporal lobar degeneration (FTLD) subtypes and differentiate FTLD from non-amnestic Alzheimer's disease. The 3-year project aims to use optical coherence tomography to identify retinal abnormalities that may serve as non-invasive biomarkers for the underlying tau, TDP-43, or...

Summary The National Eye Institute (NEI), under its Vision Research program (CFDA 93.867), awarded $417,162 to the University of Houston System for a two-year project (July 1, 2025 – June 30, 2027) investigating the birefringence properties of the lamina cribrosa and posterior eye structures as they relate to glaucoma detection and diagnosis. The project addresses a critical clinical need by developing advanced optical imaging methodologies to detect early structural and stress-related changes...

Federal Grant Award Summary The Oklahoma Medical Research Foundation (OMRF) received a $468,875 Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), effective May 1, 2026, through April 30, 2028. This award funds mechanistic investigations into tryptophan catabolites and their role in improving vision outcomes for individuals with multiple sclerosis (MS). The research focuses on understanding how a ketogenic diet restores visual function...