Project Grant R21EY037546
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded a $896,500 Vision Research (CFDA 93.867) Project Grant to The Research Foundation For The State University of New York, operating as Upstate Medical Center, beginning September 1, 2025, with completion scheduled for August 31, 2027. This research project investigates the regulation of eye progenitor epithelium morphology and the molecular mechanisms underlying congenital eye malformations, specifically examining the...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded $255,340 through the Vision Research program (CFDA 93.867) to The Regents of the University of California, San Francisco for a five-year project (May 1, 2026 – April 30, 2031) focused on understanding and regenerating retinal ganglion cells in the vertebrate retina. This research addresses glaucoma, which affects over four million Americans and represents the second leading cause of irreversible blindness globally. The...
- Federal Grant Award Summary The National Eye Institute awarded The Research Foundation For The State University of New York (RF SUNY), operating as Upstate Medical Center, a Project Grant of $896,500 under the Vision Research program (CFDA 93.867) to investigate the transcriptional dynamics of photoreceptor gene regulation. The award, effective September 1, 2025, through August 31, 2027, will deliver research products characterizing the nuclear dynamics of the homeodomain transcription factor...
- Federal Project Grant Award Summary The National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) awarded $902,000 to the University of California, San Francisco for a two-year project (September 1, 2025 – August 31, 2027) to conduct multimodal characterization of a novel inherited mouse model of glaucoma. The primary deliverables include comprehensive phenotypic characterization of GLIS1 knockout mice across two genetic backgrounds, evaluating structural and functional...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded The Johns Hopkins University a Vision Research grant (CFDA 93.867) totaling $173,286.17 to evaluate the regenerative potential of human retinal ganglion cells (RGCs). This project, which commenced June 1, 2025, addresses a critical barrier to vision restoration by investigating whether intrinsic factors regulating RGC survival and neurite outgrowth can be modulated to promote axonal regeneration and optic nerve...
- Federal Project Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $218,456 to Upstate Medical University through The Research Foundation For The State University Of New York to establish a Training Program in Molecular and Translational Visual Sciences (MTVS). The five-year project, initiated August 1, 2025 and concluding July 31, 2030, will train four doctoral students—three pursuing Ph.D. degrees and one pursuing a dual MD/PhD...
- Federal Grant Award Summary The National Eye Institute (NEI), under its Vision Research program (CFDA 93.867), awarded the University of Rochester $160,448 for a project grant commencing May 1, 2026, and concluding August 31, 2028. The research investigates the spatial and temporal dynamics of neural interactions underlying attention-related enhancement and suppression of visual processing. This foundational neuroscience research addresses critical gaps in understanding visuospatial attention...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded The Johns Hopkins University a Project Grant totaling $199,122.50 (awarded June 1, 2025) under the Vision Research program (CFDA 93.867) to support fundamental research on starburst amacrine cells (SACs) in human retinal organoids. The project will deliver scientific research products including empirical findings on the developmental mechanisms and cellular connectivity of SACs, which are specialized interneurons critical to...
- Summary of Federal Project Grant Award The National Eye Institute (NEI) awarded a $422,125 Project Grant to the University of Miami's Office of Research Administration—School of Medicine on August 1, 2025, under the Vision Research program (CFDA 93.867) for a two-year project period concluding July 31, 2027. This award funds research investigating cholesterol homeostasis as a therapeutic target for demyelinating eye diseases, which are pathologies affecting the optic nerve that can cause...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded the University of California, Davis $423,767 under the Vision Research program (CFDA 93.867) for a two-year project period beginning June 1, 2025 and concluding May 31, 2027. The research project investigates the role of myeloid cells as mediators of glaucomatous axon degeneration and evaluates whether nicotinamide adenine dinucleotide (NAD+)-boosting interventions provide neuroprotection through anti-inflammatory...
The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $440,275 to The Research Foundation for the State University of New York for a two-year project (April 1, 2026 through March 31, 2028) to investigate the interacting proteins involved in retinal ganglion cell (RGC) genesis. The research focuses on identifying and characterizing factors that interact with ATOH7, a transcription factor essential for RGC development during embryonic stages. By elucidating the mechanisms by which ATOH7 and its interacting proteins regulate RGC formation, this project aims to generate fundamental knowledge that will facilitate future efforts to reprogram stem cells and glial cells into functional RGCs to treat RGC degeneration diseases such as glaucoma and hereditary optic neuropathies. The project deliverables include empirical research findings from both ex vivo and in vivo assays examining ATOH7 protein interactions and functional domains, with the ultimate goal of contributing to therapeutic strategies for reversing RGC loss in patients with vision-impairing diseases. Research will be conducted at the University at Buffalo location in Buffalo, NY 14203, with administrative support provided through RF SUNY's Sponsored Programs Services organization.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $440.3k | 4/2/26 |