Project Grant DP2AI190432
Award Date
9/3/24
Completion Date
8/31/27
Dollars Obligated
$1.5M
Funding Federal Agency
Office of the Director
Awarding Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.310
Assistance Type
Project Grant
Place of Performance
New York, NY 10032, USA
Similar Awards
This federal Project Grant award R01AI183599 in the amount of $1,553,810 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research to evaluate a genomic surveillance approach for monitoring the emergence of artemisinin resistance in Plasmodium falciparum malaria parasites in Africa. The key objectives are to: 1) identify parasite genetic loci under selection over time...
This Project Grant award of $791,864, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to identify the molecular factors that control chromatin organization and gene regulation in the malaria parasite Plasmodium falciparum. The primary goal is to elucidate the importance of long non-coding RNAs (lncRNAs) in parasite development, virulence, and sexual differentiation, and...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $375,000.00 in funding to the University of South Florida to conduct research on the functions of messenger ribonucleoproteins (mRNPs) in regulating RNA metabolism in the malaria parasite Plasmodium falciparum. The key objectives of this 5-year research project are to: 1) identify molecular markers for distinct mRNP...
This is a Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $1,373,790 grant supports research to develop a next generation of antimalarial compounds called ELQs (endochin-like quinolones) that can provide once-monthly oral protection against malaria. Key objectives include optimizing the structural features of the lead compound ELQ-596 to enhance its anti-plasmodial activity,...
This $147,656 federal Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand the role of transmembrane proteins in the cell division process of the malaria parasite Plasmodium falciparum. The award, effective January 22, 2025 through October 31, 2027, will enable the integration of biochemical and super-resolution microscopy approaches to decipher...
The federal Project Grant award of $459,131, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) program, supports research to identify essential functions of the mitochondrion in malaria parasites. The goal is to uncover novel drug targets within the parasite mitochondrion that could lead to the development of new antimalarial treatments effective against both symptomatic and transmission stages of malaria...
This Project Grant award of $153,056.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research into understanding heme homeostasis mechanisms in the malaria parasite Plasmodium falciparum. The key objectives are to: 1) Identify parasite heme-binding proteins using a click-chemistry based approach and assess their essentiality through conditional knockdown experiments, and 2) Investigate...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,399,125 Project Grant to The Regents of the University of California, doing business as the University of California, Berkeley, under the NIGMS Biomedical Research and Research Training program (CFDA 93.859). The grant aims to decode the molecular processes that regulate circadian rhythms in malaria parasites and discover how disrupting their regulatory networks impacts malaria pathogenesis and transmission. The project will...
This $215,751 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to identify and characterize RNA-binding proteins (RBPs) and RNA-dependent proteins (RDPs) in the malaria parasite Plasmodium falciparum. The research team at the University of California, Riverside will use an unbiased proteome-wide approach, called R-DEEP, to detect RBPs and RDPs during the parasite's sexual...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,104,050 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Washington University in St. Louis. The grant will fund research to investigate the molecular mechanisms by which the Plasmodium falciparum malaria parasite's secreted histidine-rich protein II (HRPII) impairs the function of human neutrophils, a critical component of the immune response. The goal is to elucidate...