Project Grant R01AI188634
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $445,488 in funding to the University of Maryland, Baltimore (UMB) to conduct research on the role of long non-coding RNAs (lncRNAs) in regulating gene expression in the malaria parasite Plasmodium falciparum. The research aims to gain a comprehensive understanding of how lncRNAs influence the regulation of neighboring...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $375,000 in funding to the University of South Florida to conduct research on the functions of mRNA-binding proteins in the malaria parasite Plasmodium falciparum. The research aims to identify molecular markers for different types of mRNA granules, determine their protein and mRNA compositions, and...
- The Project Grant award R01AI187153 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on identifying genetic factors associated with sexual stage development (gametocyte formation) in the malaria parasite Plasmodium falciparum. The $700,288 award, with a project period from Nov 2024 to Oct 2029, will fund a research project at the University of South Florida to perform...
- This $147,656 federal Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand the role of transmembrane proteins in the cell division process of the malaria parasite Plasmodium falciparum. The award, effective January 22, 2025 through October 31, 2027, will enable the integration of biochemical and super-resolution microscopy approaches to decipher...
- This $230,808 project grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) program. The grant supports research by Washington University in St. Louis to investigate heme homeostasis mechanisms in the malaria parasite Plasmodium falciparum. The project aims to identify parasite heme-binding proteins and assess their essentiality for parasite viability, as well as examine the role of the heme...
- This $633,218 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to characterize the mechanism of inhibition of the malaria parasite protein PFNCR1 by new small molecule inhibitors. The research aims to gain a better understanding of the contact region between the parasite plasma membrane and parasitophorous vacuolar membrane, where PFNCR1 resides, using structural, physiological,...
- This $1,480,500 federal Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) will fund research by The Trustees of Columbia University in the City of New York to identify and characterize the roles of non-coding RNAs in regulating drug-induced quiescence in Plasmodium falciparum, the parasite that causes malaria. The project aims to uncover novel epigenetic and epitranscriptomic mechanisms that enable...
- The University of Georgia Research Foundation was awarded a $540,193 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The 12-month award, effective August 22, 2023, supports research to investigate the role of calcium-binding proteins and other secretory pathway components in the exocytosis of organelles critical for the invasion and egress of the malaria parasite Plasmodium falciparum...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $813,160 to George Washington University to develop mRNA-LNP combination vaccines targeting multiple stages and species of the human malaria parasite. The grant aims to evaluate the protective efficacy of various vaccine antigens, including PFS25, PFS230, PFCSP, PVS25, and a chimeric PVCSP, both individually...
- This federal Project Grant award of $107,542 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Washington University. The grant supports research to unravel the mechanisms underlying the differential sorting and trafficking of Plasmodium falciparum proteins secreted during the symptomatic stage of malaria. The research aims to determine how exported proteins are selectively targeted...
This federal Project Grant award of $791,864 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to identify molecular factors controlling chromatin organization and gene regulation in the malaria parasite Plasmodium falciparum. The research aims to elucidate the importance of long non-coding RNAs (lncRNAs) in parasite development, virulence, and sexual differentiation, with the goal of identifying potential therapeutic targets. The award, effective December 1, 2024 through November 30, 2029, includes sub-awards to the University of Washington, Stowers Institute for Medical Research, and the University of Georgia Research Foundation to conduct complementary genomic, molecular, and cellular approaches. The findings are expected to provide groundbreaking insights into parasite-specific lncRNAs and their role in controlling malaria biology, leading to new directions in malaria research and therapy.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $791.9k | 11/19/24 |
GrantNumber | Description | Subgrantee | Prime Award | Dollars Obligated | Updated At |
|---|---|---|---|---|---|
S1898S | University Of Washington | Project Grant R01AI188634 | $167.6k | 3/19/25 | |
S1897S | Stowers Institute For Medical Research | Project Grant R01AI188634 | $44.8k | 3/12/25 | |
S1899S | University Of Georgia Research Foundation, Inc. | Project Grant R01AI188634 | $58.6k | 2/21/25 |