The National Institute of General Medical Sciences (NIGMS) awarded a $1,399,125 Project Grant to The Regents of the University of California, doing business as the University of California, Berkeley, under the NIGMS Biomedical Research and Research Training program (CFDA 93.859). The grant aims to decode the molecular processes that regulate circadian rhythms in malaria parasites and discover how disrupting their regulatory networks impacts malaria pathogenesis and transmission. The project will leverage forward-genetics screens, behavioral, molecular, and bioinformatic approaches to identify the molecular machinery of malaria parasites' intrinsic clocks. This research could unravel insights into the mechanism behind malaria's characteristic rhythmic fevers and provide new targets to disrupt the rhythms that contribute to the disease. The grant has an award date of September 25, 2023 and an ultimate completion date of August 31, 2026.
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