Project Grant 2613931
- This $1,269,993 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research to understand the molecular basis of how plant cells establish the division plane during cell division. The project aims to dissect the function of cytoskeletal motor assemblies at the cortical division site and determine how they connect to molecules in the phragmoplast, the structure that forms the new cell wall during cytokinesis. Researchers at...
- This federal Project Grant award of $946,895 from the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences (CFDA 47.074 Biological Sciences) will fund research to advance the understanding of protein phosphorylation and its role in coordinating cell division. The project aims to identify new enzymes that carry out phosphorylation and the substrate proteins they modify to ensure proper cell division. Researchers will employ computational, biochemical, proteomic,...
- This four-year Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences provides $885,852 to Oregon Health & Science University under the Biological Sciences program (CFDA 47.074) from August 2021 through July 2025. The funding supports quantitative exploration of molecular machine mechanisms to advance understanding of major challenges in biology. As the stated purpose of the Biological Sciences program is to promote progress in the field and...
- This National Science Foundation (NSF) Biological Sciences program project grant, awarded to Oregon Health & Science University (OHSU), aims to uncover the underlying biophysical mechanisms of directed cell migration. The $1,049,497 grant, with a period of performance from January 2024 to December 2027, will examine how actin cytoskeletal networks and adhesion receptors interact as interdependent subsystems to facilitate matrix-guided cell migration, which is crucial for tissue formation and...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Colorado State University Sponsored Programs Division a $949,949 Project Grant under the Biological Sciences (CFDA 47.074) federal grant program. The award period is from June 15, 2023 through May 31, 2027. Through this funding, Colorado State University will investigate the cellular machinery that carries out endocytosis, a process by which cells take up nutrients and communicate. Researchers will study...
- This National Science Foundation (NSF) Division of Molecular and Cellular Biosciences Project Grant, titled "TUNING MICROTUBULE-ACTIN CROSSTALK TO CONTROL MITOTIC FIDELITY", will provide $488,281 in funding to the University of Washington from August 1, 2023 to July 31, 2026. The project aims to describe a biological phenomenon where small changes in microtubule assembly temporarily promote the delivery of molecules that interfere with the mitotic spindle's ability to properly position...
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $1.1M to the University of California, Davis under the Biological Sciences program (CFDA 47.074) to conduct fundamental research investigating how cytokinin hormonal signaling regulates cell plate development and callose deposition during plant cell division. The project, which commenced August 1, 2025, and concludes July 31, 2028, will deliver mechanistic insights into...
- This National Science Foundation award provides $1,656,474 to the University of Colorado Boulder through May 2026 to develop mathematical models of mitosis under the Biological Sciences grant program (CFDA 47.074). The university will build on previous work modeling chromosome segregation during cell division to create a new model integrating deformable nuclear envelope dynamics. Researchers aim to identify how forces within the nuclear envelope drive successful chromosome separation during...
- This Project Grant award of $1.13M from the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074), effective September 1, 2025 through August 31, 2028, supports research on cytoskeletal regulation of single cell migration in complex environments. The primary deliverable is fundamental research examining how septin proteins function in cell migration through constrained spaces, with applications to both human immune system cells and Caenorhabditis elegans (nematode...
- Oregon State University was awarded a $1,209,960 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences on June 1, 2021, with a completion date of May 31, 2025. The grant is being used to support research under the Biological Sciences (CFDA 47.074) federal grant program. Specifically, the funding will support development of ideal eukaryotic tetrazine ligations for imaging protein dynamics in live cells. The goal is to advance scientific understanding of...
The National Science Foundation's Division of Molecular and Cellular Biosciences awarded the University of Oregon a $1.13 million Project Grant on July 15, 2026, under the Biological Sciences program (CFDA 47.074) to investigate mechanisms controlling cytokinesis-related protein activation. The research will employ biochemical and single-molecule imaging methods to elucidate how the guanine nucleotide exchange factor ECT2 and the GTPase-activating protein CYK4 regulate RHO1 activity during cell division on reconstituted membrane surfaces. The project extends through June 30, 2029, and focuses on filling critical knowledge gaps regarding membrane localization and regulation of cytokinetic proteins to prevent errors in cell division that can lead to genomic instability and disease. Beyond the core research objectives, the grant funds workforce development and public engagement activities. The award provides early-career scientists training in advanced techniques including single-molecule imaging, structural biochemistry, enzyme kinetics, and quantitative image analysis, with mentorship in science communication and leadership skills. The principal investigator's team will develop microscopy-based learning modules for K-12 and public outreach education that communicate the relevance of cellular process research to human health and disease prevention.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.1m | 7/9/26 |