This National Science Foundation (NSF) Division of Molecular and Cellular Biosciences Project Grant, titled "TUNING MICROTUBULE-ACTIN CROSSTALK TO CONTROL MITOTIC FIDELITY", will provide $488,281 in funding to the University of Washington from August 1, 2023 to July 31, 2026. The project aims to describe a biological phenomenon where small changes in microtubule assembly temporarily promote the delivery of molecules that interfere with the mitotic spindle's ability to properly position itself, leading to errors in cell division. The research will employ high-resolution live imaging, atomic force microscopy, and actin reporters to observe this process and correlate it with segregation errors using super-resolution expansion microscopy. This work is part of the NSF's Biological Sciences program (CFDA 47.074), which seeks to promote progress in the biological sciences and enhance understanding of major problems confronting the nation. The project includes collaboration between researchers at the University of Washington and in Germany, with the NSF funding the U.S. investigator and the Deutsche Forschungsgemeinschaft (DFG) funding the German partner.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $488.3k | 7/27/23 |