Project Grant 2610165
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $800,000 Project Grant to the University of California, San Diego on June 15, 2026, for collaborative research on transcriptome-wide visualization and functional characterization of RNA tertiary structures in human cells. Under this award, funded through the Biological Sciences program (CFDA 47.074) with a completion date of May 31, 2029, the research team will...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $1.2 million to the University of California, Davis under the Biological Sciences program (CFDA 47.074) on July 15, 2026, with a completion date of June 30, 2030. This Project Grant supports fundamental research into gene-specific nuclear messenger ribonucleoprotein (mRNP) assembly and quality control mechanisms. The research focuses on understanding how genetic...
- Federal Project Grant Award Summary The University of California, San Diego received a $700,000 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective August 1, 2025, through July 31, 2028. This award funds fundamental research to elucidate the molecular mechanisms of riboswitch-based gene regulation in manganese ion transporters. The project will map the co-transcriptional folding...
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded a $849,969 Project Grant to the University of Cincinnati on August 1, 2025, under the Biological Sciences program (CFDA 47.074) to conduct fundamental research on microtubule lattice allostery and protein-protein interactions. The four-year research initiative (through July 31, 2029) employs multi-scale computational modeling, machine learning, and experimental...
- Federal Project Grant Award Summary The University of California, Santa Barbara received a $514,198 Project Grant from the National Science Foundation (NSF) Division of Materials Research under the Mathematical and Physical Sciences program (CFDA 47.049) for collaborative research on mesoscopic properties of multi-phase biomolecular liquids. The award period runs from July 1, 2026 through June 30, 2029. The research will deliver experimental and theoretical investigations into how cells organize...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a collaborative research project grant of $171,000 to The Regents of the University of Colorado on June 15, 2026, under the Biological Sciences program (CFDA 47.074). The project, "Collaborative Research: Long-Range Signaling and Computation in Microtubules," will be executed through May 31, 2029. This project grant supports basic research investigating a...
- Federal Project Grant Award Summary The National Science Foundation's Division of Chemistry is funding a $749,999 Project Grant awarded September 1, 2025, through the Mathematical and Physical Sciences program (CFDA 47.049) to develop advanced methodologies for dynamic cellular RNA imaging. The award supports collaborative research between Dr. Ralph Kleiner at Princeton University and Dr. Byron Purse at San Diego State University to create a generalizable approach for tracking RNA synthesis,...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Regents of the University of California, San Francisco a $1.453 million Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) on September 5, 2025, with completion anticipated on May 31, 2030. This award supports research aimed at bridging the gap between structural prediction and experimental reality in structural biology by developing advanced simulation-based...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $193,684 Project Grant to the University of Georgia Research Foundation effective September 1, 2025, through August 31, 2029, under the Biological Sciences program (CFDA 47.074). This collaborative research initiative investigates the mechanisms by which polo kinases maintain chiral asymmetry and support complex organizational patterning in Tetrahymena thermophila, a...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Materials Research awarded $329,197 to the University of California, Santa Barbara (UCSB) under the Mathematical and Physical Sciences program (CFDA 47.049) for a three-year project spanning September 1, 2025, through August 31, 2028. The research initiative, "Active Assembly—Creating Elastic Networks with an Active Fluid," develops an innovative materials synthesis approach that uses spontaneously...
The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $967,237 to the University of California, Santa Barbara on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to investigate the mesoscale biophysics of Arginine-Glycine-Glycine (RGG)/RNA interactions. This four-year project, extending through May 31, 2030, will deliver fundamental research establishing quantitative physical principles governing how RGG motifs—the second most common RNA-binding domain in the human proteome—interact with ribonucleic acid molecules. Using an integrated approach combining single-molecule mechanical manipulation via custom-built magnetic tweezers, bulk phase behavior analysis, and computational modeling, the research will characterize how sequence features, valence, aromatic residue content, and ionic conditions dictate binding affinities and structural outcomes. Beyond the core research deliverables, this project will advance STEM education and workforce development through hands-on training of graduate and undergraduate students in single-molecule instrumentation and biochemistry. The research outcomes are expected to inform the design of responsive biomaterials with programmable properties and synthetic protocells, while advancing understanding of protein-RNA dysfunction implicated in human disease. As a Project Grant within NSF's highly active Biological Sciences program, this award represents core support for basic research strengthening the Nation's scientific enterprise through fundamental investigation of critical cellular processes.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $967.2k | 6/16/26 |