Project Grant 2550997
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $1.2 million to the University of California, Davis under the Biological Sciences program (CFDA 47.074) on July 15, 2026, with a completion date of June 30, 2030. This Project Grant supports fundamental research into gene-specific nuclear messenger ribonucleoprotein (mRNP) assembly and quality control mechanisms. The research focuses on understanding how genetic...
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $967,237 to the University of California, Santa Barbara on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to investigate the mesoscale biophysics of Arginine-Glycine-Glycine (RGG)/RNA interactions. This four-year project, extending through May 31, 2030, will deliver fundamental research establishing quantitative physical principles governing how RGG...
- Federal Project Grant Award Summary The University of California, San Diego received a $700,000 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective August 1, 2025, through July 31, 2028. This award funds fundamental research to elucidate the molecular mechanisms of riboswitch-based gene regulation in manganese ion transporters. The project will map the co-transcriptional folding...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received an $800,000 Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), awarded June 15, 2026, with completion targeted for May 31, 2029. This collaborative research initiative delivers systematic discovery, characterization, and high-resolution structural determination of RNA tertiary structures in human cells using...
- Federal Project Grant Award Summary The National Science Foundation's Division of Chemistry is funding a $749,999 Project Grant awarded September 1, 2025, through the Mathematical and Physical Sciences program (CFDA 47.049) to develop advanced methodologies for dynamic cellular RNA imaging. The award supports collaborative research between Dr. Ralph Kleiner at Princeton University and Dr. Byron Purse at San Diego State University to create a generalizable approach for tracking RNA synthesis,...
- Federal Grant Award Summary The University of California, San Diego received a $375,000 Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074). The four-year award, active from August 1, 2025 through July 31, 2029, supports collaborative research investigating analog information storage in chromatin states—specifically how cells maintain identity information through gene expression regulation...
- Federal Grant Award Summary The Division of Mathematical Sciences (DMS), part of the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049), awarded $500,000 to the University of California, Irvine for a three-year project (August 1, 2025 – July 31, 2028) titled "Decoding RNA Splicing Dynamics from Static Images Using Mechanistic Stochastic Modeling." This research combines experimental and computational approaches to understand RNA splicing—a...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $900,000 Project Grant to the University of Pennsylvania on September 15, 2025, with completion targeted for August 31, 2028. This collaborative research initiative, funded under the Biological Sciences program (CFDA 47.074), investigates the mechanism of transcription factor (TF) functional divergence through "differential usage of shared binding sites"...
- Federal Grant Award Summary The Leland Stanford Junior University received a $384,999 Project Grant award dated August 6, 2025, through the Trans-NIH Research Support program (CFDA 93.310) administered by the National Institutes of Health Office of the Director. The award supports a five-year research initiative (completion date: July 31, 2030) titled "Deciphering the Principles and Mechanism of RNA Structure," which aims to advance computational and biophysical methodologies for...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Biological Infrastructure awarded $1.2 million to the University of California, San Diego under the Biological Sciences program (CFDA 47.074) to develop advanced computational tools for peptide sequencing analysis. Initiated November 1, 2025, and extending through October 31, 2029, this Project Grant funds the creation of novel algorithms and software designed to overcome current limitations in mass...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $800,000 Project Grant to the University of California, San Diego on June 15, 2026, for collaborative research on transcriptome-wide visualization and functional characterization of RNA tertiary structures in human cells. Under this award, funded through the Biological Sciences program (CFDA 47.074) with a completion date of May 31, 2029, the research team will systematically identify, characterize, and solve high-resolution three-dimensional structures of previously unknown RNA tertiary motifs using innovative chemical probing technology. Specific research deliverables include investigation of functional roles of RNA tertiary structures in transcription factor genes and evaluation of regulatory impacts in 5'-untranslated regions through massively parallel reporter assays. The grant supports fundamental scientific discovery with applications toward advancing gene regulation knowledge and developing RNA-targeted medicines. Additionally, the project will generate three-dimensional RNA structural data to support artificial intelligence modeling efforts for predicting RNA structures, analogous to recent breakthroughs in protein folding prediction. The award includes workforce development components, training undergraduate researchers in collaborative team science to strengthen the nation's biotechnology workforce in this strategically important research area.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $800.0k | 6/26/26 |