Project Grant 2540468
- Federal Project Grant Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $478,840 to The Regents of the University of Colorado (University of Colorado-Denver) on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to support collaborative research on long-range signaling and computation in microtubules. The project, which runs through May 31, 2029, will deliver fundamental research integrating computational modeling with...
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded Massachusetts General Hospital $298,662 on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to conduct collaborative research on long-range signaling and computation in microtubules. The research project, scheduled for completion by May 31, 2029, will deliver fundamental scientific findings and methodologies challenging the conventional understanding of...
- Federal Project Grant Award Summary Rensselaer Polytechnic Institute received a $251,498 Project Grant award from the National Science Foundation (NSF), Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074) on June 15, 2026. The award supports collaborative research investigating long-range signaling and computation in microtubules, with work to be completed by May 31, 2029. The research will deliver fundamental scientific knowledge through an...
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded a $849,969 Project Grant to the University of Cincinnati on August 1, 2025, under the Biological Sciences program (CFDA 47.074) to conduct fundamental research on microtubule lattice allostery and protein-protein interactions. The four-year research initiative (through July 31, 2029) employs multi-scale computational modeling, machine learning, and experimental...
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $1.49M to The Regents of the University of Colorado (Boulder) under the Biological Sciences program (CFDA 47.074) on June 15, 2026, with completion scheduled for May 31, 2030. This collaborative research project focuses on elucidating the regulatory mechanisms of cyclin-dependent kinase 7 (CDK7) in controlling RNA polymerase II (RNAPII) transcription termination and RNA...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $193,684 Project Grant to the University of Georgia Research Foundation effective September 1, 2025, through August 31, 2029, under the Biological Sciences program (CFDA 47.074). This collaborative research initiative investigates the mechanisms by which polo kinases maintain chiral asymmetry and support complex organizational patterning in Tetrahymena thermophila, a...
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $967,237 to the University of California, Santa Barbara on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to investigate the mesoscale biophysics of Arginine-Glycine-Glycine (RGG)/RNA interactions. This four-year project, extending through May 31, 2030, will deliver fundamental research establishing quantitative physical principles governing how RGG...
- Federal Project Grant Award Summary The Johns Hopkins University received a $999,993 Project Grant awarded August 1, 2025, through the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074). The award supports fundamental research investigating the assembly and regulation mechanisms of filamentous signaling platforms—large supramolecular protein structures that coordinate cellular signaling responses and regulate complex...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $1.2 million to the University of California, Davis under the Biological Sciences program (CFDA 47.074) on July 15, 2026, with a completion date of June 30, 2030. This Project Grant supports fundamental research into gene-specific nuclear messenger ribonucleoprotein (mRNP) assembly and quality control mechanisms. The research focuses on understanding how genetic...
- Federal Grant Award Summary The University of California, Berkeley received a $951,106 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective June 1, 2026 through May 31, 2029. This award funds fundamental research to elucidate the regulatory mechanisms by which microtubule-associated proteins (MAPs) control kinesin motor protein activity during intracellular cargo transport. The project...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a collaborative research project grant of $171,000 to The Regents of the University of Colorado on June 15, 2026, under the Biological Sciences program (CFDA 47.074). The project, "Collaborative Research: Long-Range Signaling and Computation in Microtubules," will be executed through May 31, 2029. This project grant supports basic research investigating a novel hypothesis that microtubule polymers function as transmitters and amplifiers of conformational signals within cells, challenging the conventional view of microtubules as purely structural elements. The research deliverables will include computational modeling and experimental validation at single-molecule and cellular levels to test mechanisms of signal propagation along microtubule structures. The project is expected to generate foundational knowledge with applications extending across multiple scientific domains, including potential impacts on neuronal communication mechanisms, cancer treatment resistance, and bioengineering applications involving microtubule-based molecular computation. Results will advance the understanding of cellular communication pathways and may inform new therapeutic strategies in oncology and neuroscience.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $171.0k | 6/25/26 |