Project Grant 2540152
- Federal Grant Award Summary New York University received a $355,000 Project Grant award from the National Science Foundation (NSF) Division of Computing and Communication Foundations under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070), effective September 1, 2025, through August 31, 2028. This collaborative research initiative focuses on developing algorithmic shape encoding at the nanoscale by creating mathematical and computational tools to distinguish and...
- Federal Grant Award Summary New York University received a $2.398 million Project Grant award dated September 1, 2025, from the Department of Energy's Office of Science under the Office of Science Financial Assistance Program (CFDA 81.049). The award supports fundamental research on "Genome-Scale Mapping and Functional Characterization of Cis-Regulatory Networks in Cellular Reprogramming and Regeneration," with a project completion date of August 31, 2026. The research will be...
- Federal Project Grant Summary The National Science Foundation (NSF) Division of Chemistry awarded a $600,000 project grant to New York University (NYU) and NYU Langone Health, effective September 1, 2025, through August 31, 2028, under the Mathematical and Physical Sciences (CFDA 47.049) program. Led by Dr. Oded Regev and Dr. Jef Boeke, the project develops PolySnap-Seq, a novel experimental methodology to determine the spatial organization and positioning of ribosomes along individual RNA...
- Federal Project Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded $750,000 on April 15, 2025, under the Biological Sciences program (CFDA 47.074) to The Research Foundation For The State University Of New York at the University at Albany to develop manufacturable three-dimensional (3D) mammalian cell culture systems with integrated sensing technologies, with completion targeted for March 31, 2029. The primary research deliverables...
- Federal Project Grant Award Summary The Trustees of Boston University received a $885,642 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences (Biological Sciences Program, CFDA 47.074) effective September 1, 2025, through August 31, 2028. The award supports research to characterize signal propagation and control within gene regulatory networks using optogenetic techniques. The primary deliverables include foundational scientific knowledge regarding...
- Federal Project Grant Award Summary MIT received $1,041,774 in funding from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) for a collaborative research project running from August 1, 2025, through July 31, 2029. This project grant supports fundamental research investigating analog information storage in chromatin states, with the goal of understanding how cells encode and maintain their identity through...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded the University of Washington a $836,598 Project Grant (CFDA 47.074, Biological Sciences) effective September 1, 2025, through August 31, 2030. This CAREER award funds research to develop tools and methodologies for reading and sequencing expanded genetic alphabets (XNA) containing synthetic nucleotide bases beyond the standard adenine, thymine, guanine, and cytosine. The...
- Federal Grant Award Summary New York University received a $2.13 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025 through August 31, 2029. The award supports fundamental research investigating the structural dynamics of the long noncoding RNA (lncRNA) FIRRE and its relationship to biological function. The research team will employ integrated expertise in...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Research Foundation for the State University of New York a $2.2 million Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to support fundamental research on transcription factor binding to chromosomal DNA. The grant, awarded on September 20, 2025, with completion targeted for August 31, 2029, funds investigations into how transcription factors—particularly...
- Federal Grant Award Summary The University of California, San Diego received a $375,000 Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074). The four-year award, active from August 1, 2025 through July 31, 2029, supports collaborative research investigating analog information storage in chromatin states—specifically how cells maintain identity information through gene expression regulation...
Award Details: Project Overview: New York University will conduct fundamental research and development under the SYNTACS (Synthetic Transcriptional Architecture of Condensates and Super-Enhancers) project to establish design principles governing genome architecture and gene regulation in human cells. The research will systematically re-engineer the spacing, density, and orientation of regulatory DNA elements within large genomic regions (>100 kilobases) using the REWRITE platform for programmable DNA restructuring in human induced pluripotent stem cells. By testing the hypothesis that linear organization of super-enhancers controls transcriptional output through transcription factor condensate dynamics and chromatin topology, this work aims to advance predictive and design capabilities for engineered genomic systems with applications in regenerative medicine, immune engineering, and biomanufacturing. In parallel with research activities, the project integrates educational and workforce development through a tiered training program encompassing middle school laboratory visits, undergraduate and master's research opportunities, and graduate student training. These combined research and educational outputs will contribute to development of skilled biotechnology professionals while advancing fundamental understanding of how genetic regulatory information is encoded in DNA structure.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.3m | 4/22/26 |