The National Science Foundation (NSF) awarded a $2,249,999 Project Grant under the Engineering program (CFDA 47.041) to The Research Foundation for the State University of New York (RF-SUNY) at the University at Albany. The objective of this 4-year project, ending on March 31, 2029, is to develop manufacturable 3D mammalian cell culture systems with integrated sensing technologies, particularly focused on neural organoids. The key research activities include: 1) Building and testing conformal microelectrode arrays to interrogate neural organoids and transitioning these to flexible electronics manufacturing; 2) Developing photonic-based sensors to detect small molecule metabolites using DNA aptamers; and 3) Optimizing production of photonic hydrogels for pressure/strain sensing and integration with photonic devices. In parallel, the project will engage in workforce development activities, such as STEM outreach to middle school students and technical training combining life sciences, engineering, and device design. The project aims to address challenges related to manufacturability of scaled-down sensing devices, incorporating photonic/electronic sensing in 3D culture systems, and integrating photonic hydrogels to support cell growth and sensing.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $2.2m | 6/4/25 |