Project Grant 2448313
Award Date
8/1/25
Completion Date
7/31/29
Dollars Obligated
$375K
Federal Agency
Division of Molecular and Cellular Biosciences
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
La Jolla, CA 92093, USA
Similar Awards
This federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) program provides $1,041,774 to the Massachusetts Institute of Technology (MIT) for a collaborative research project focused on investigating the biological mechanisms that enable analog information storage in the chromatin state of cells. The primary objectives are to develop a model-driven, built-to-understand approach to dissect the molecular mechanisms governing analog versus binary...
This National Science Foundation project grant award of $600,000 supports research into the mechanisms underlying long-term memory storage at the University of California, Los Angeles from February 1, 2022 to January 31, 2025. The award is made under the Biological Sciences program (CFDA 47.074) to promote progress in the biological sciences. Specifically, the grant funds research investigating whether memories are stored through nuclear modifications in neurons rather than changes in...
The National Science Foundation awarded a two-year $299,986 Project Grant to the University of California, Davis under the Biological Sciences federal grant program (CFDA 47.074) from June 2023 to May 2025. The grant will support development of a new method to measure genome-wide targeting of histone readers, proteins that bind histone modifications to translate epigenetic codes into biological processes. If successful, the tool could help decipher how histones orchestrate genome and organism...
This Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program provides $900,000 to The Regents of the University of Colorado (CU) to conduct research on the molecular mechanisms underlying the DNA methyltransferase 1 (DNMT1) enzyme's role in inheritance of gene silencing. The project aims to utilize structural biology, biochemistry, and cell biology methods to understand DNMT1 regulation and the mechanism cells use to restrict DNMT1...
This National Science Foundation project grant of $1,011,518 supports collaborative research between the University of California, San Diego and the State of California Controller's Office to discover the principles of active self-organization in the differentiating genome. The award period is from July 1, 2022 through June 30, 2026 under the Mathematical and Physical Sciences program (CFDA 47.049). The project will integrate state-of-the-art live cell experiments with multiscale mathematical...
This $1,220,400 Project Grant awarded by the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences supports a collaborative research project between investigators in the U.S. and U.K. to better understand the regulatory mechanisms controlling mammalian gene expression. The project, funded through NSF's Biological Sciences program (CFDA 47.074), aims to define the roles of different DNA regulatory elements and how they work together to precisely control gene expression....
The University of California, San Diego received a $300,000 Project Grant award from the National Science Foundation on February 1, 2021 to develop a high-throughput in vivo method for measuring transcription factor-DNA interactions. The grant supports research under the NSF's Biological Sciences program (CFDA 47.074) through January 31, 2023. The Biological Sciences program aims to advance the fundamental biological sciences and enhance understanding of major problems through basic research....
This Project Grant award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) provides $481,237 to the Massachusetts Institute of Technology (MIT) to develop reversible long-term memory devices in bacterial cells. The key products and services to be delivered include: Demonstrating the engineering of a circuit motif in bacteria that mimics processes associated with long-term memory of chromatin states in...
This Project Grant award of $229,840.00 from the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program supports research at Brandeis University to investigate how a protein called HP1 helps cells maintain epigenetic memory. The project will use the fission yeast model organism to pursue three key objectives: (1) engineer synthetic H3K9me binding modules to test the influence of genome compartmentalization on epigenetic memory, (2) determine how...
This $573,937 five-year Project Grant was awarded on February 1, 2024 by the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074). The grant will fund research at the Massachusetts Institute of Technology (MIT) to understand how changes in DNA structure impact the behavior of synthetic gene circuits and gene expression more broadly. The project aims to develop a better understanding of supercoiling-mediated...