This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant award, valued at $570,122.00 and effective September 1, 2024, supports a collaborative research effort to investigate innate immune responses in diverse eukaryotic organisms that consume bacteria. The project brings together a cross-disciplinary team of researchers to study innate immunity in sponges, choanoflagellates, and amoebae, which span the evolutionary transition between multicellular animals and their...
This $356,334 project grant, awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074), will investigate how the antibacterial functions of neutrophil immune cells scale with body mass across diverse terrestrial mammal species. The research team from The Research Foundation For The State University Of New York will assess neutrophil activities like direct bacterial killing, phagocytosis, and generation of reactive oxygen species in mammals ranging from mice to...
The National Science Foundation (NSF) awarded a $309,184 Project Grant under the Biological Sciences (CFDA 47.074) program to the Research Foundation of the City University of New York (RFCUNY) - Medgar Evers College. The grant, effective September 1, 2024 through August 31, 2027, aims to identify key regulators of innate immunity to the rabies virus in bats. The project, led by Dr. William Carr, an expert in human innate immunity, will utilize computational biology approaches, including...
This $214,612 federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund a collaborative research project to investigate how the antimicrobial functions of immune cells, specifically neutrophils, scale with body mass in terrestrial mammals. The project, led by The Research Foundation for the State University of New York (Upstate Medical Center), aims to understand how neutrophil antibacterial responses, gene expression, and energetics...
The National Science Foundation (NSF) awarded a $458,718 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Illinois to conduct a collaborative research study on how the antimicrobial functions of immune cells, specifically neutrophils, scale with body mass in terrestrial mammals. The research will investigate how neutrophil antibacterial responses, gene expression, and energetics vary across mammalian species ranging from mice to elephants. The project aims...
This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $645,180 to North Carolina State University to conduct a collaborative research project titled "OSIB: A Multi-Omic Evaluation of Innate Immune Responses Across Vertebrate Evolution." The research aims to investigate the evolutionary history and functional diversification of the CD300 gene family, which encodes proteins playing crucial roles in immune function and disease...
The National Science Foundation (NSF) awarded a $426,255 project grant under the Biological Sciences program (CFDA 47.074) to the University of Texas at Austin to investigate the evolution of immune system development across amphibian life stages. The key objectives are to: (1) use mathematical models and empirical data to predict how evolutionary history, pathogens, and environment influence T cell diversity within and among frog life stages; (2) quantify T cell receptor diversity across...
This Project Grant award, funded by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) program, supports a collaborative research project to evaluate innate immune responses across vertebrate evolution, with a focus on the CD300 protein family. The $458,015 award to the University of North Carolina at Charlotte aims to map the molecular and functional diversification of CD300 orthologs and paralogs, and experimentally test ancestral CD300 functions. The research...
The National Science Foundation awarded a $413,329 Project Grant under the Biological Sciences (CFDA 47.074) program to the University of Colorado Boulder to support research integrating immune system and microbiome function during amphibian development from September 1, 2021 through August 31, 2024. The award will fund research examining how the immune system and microbiome interact and influence each other during amphibian growth and maturation. A subaward of $50,000 will support related...
The National Science Foundation (NSF) Division of Emerging Frontiers awarded a $613,690 Project Grant to the University of Rochester to investigate the evolution of immune investment strategies across amphibian ontogeny. The project, titled "Collaborative Research: INTBIO: The Evolution of Immune Investment Strategies Across Amphibian Ontogeny," falls under NSF's Biological Sciences (CFDA 47.074) program, which supports basic research to strengthen the nation's scientific enterprise....