This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $645,180 to North Carolina State University to conduct a collaborative research project titled "OSIB: A Multi-Omic Evaluation of Innate Immune Responses Across Vertebrate Evolution." The research aims to investigate the evolutionary history and functional diversification of the CD300 gene family, which encodes proteins playing crucial roles in immune function and disease...
This $425,486 federal Project Grant award to the University of North Carolina at Chapel Hill (UNC-CH) was made by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) program. The project aims to study the evolutionary history and functional diversification of the CD300 gene family, which encodes immune receptors implicated in human health issues like cancer, inflammation, and viral infections. Using a multi-omic approach, the research will map the molecular and...
This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $372,060 to the Research Foundation of the City University of New York (RFCUNY) - Brooklyn College will support research comparing the immune system structure, function, and memory in animal species with and without intact adaptive immune systems. The 3-year project aims to use single-cell RNA sequencing, immunization experiments, and pathogen exposure to better understand the evolutionary...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant award, valued at $570,122.00 and effective September 1, 2024, supports a collaborative research effort to investigate innate immune responses in diverse eukaryotic organisms that consume bacteria. The project brings together a cross-disciplinary team of researchers to study innate immunity in sponges, choanoflagellates, and amoebae, which span the evolutionary transition between multicellular animals and their...
This $361,227 federal Project Grant award, provided by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) program, supports research to investigate how insect immune systems interact with beneficial and pathogenic microbes across different aphid host species. The project, conducted by the University of North Carolina at Chapel Hill, aims to use transcriptome sequencing and immune assays to test the hypothesis that host immune suppression is a key mechanism enabling...
This Project Grant award from the National Science Foundation (NSF) Division of Emerging Frontiers, under the Biological Sciences program (CFDA 47.074), provides $388,992 to the University of Central Florida (UCF) to investigate the evolution of immune strategies across amphibian ontogeny. The key objectives are to: (1) use mathematical models and empirical data to predict when evolutionary history, pathogens, and environment favor T cell diversity within and among amphibian life stages; (2)...
The National Science Foundation awarded a $817,970 project grant to The University of North Carolina at Charlotte under the Biological Sciences federal grant program (CFDA 47.074) for a three-year period from May 1, 2021 to April 30, 2024. The grant will support research studying the evolution of the antiviral pathway in a cnidarian model interacting with diverse viral communities. The Biological Sciences program aims to promote progress in the biological sciences and strengthen the nation's...
This Project Grant award from the National Science Foundation (NSF) Biological Sciences Program (CFDA 47.074) is funding collaborative research led by Vanderbilt University to investigate how amphibian immune systems develop and adapt across life stages. The $274,765 project aims to: (1) use mathematical models and empirical data to understand how evolutionary history, pathogens, and environment influence T cell receptor diversity in frogs over ecological and evolutionary timescales; (2)...
The National Science Foundation (NSF) Division of Emerging Frontiers awarded a $613,690 Project Grant to the University of Rochester to investigate the evolution of immune investment strategies across amphibian ontogeny. The project, titled "Collaborative Research: INTBIO: The Evolution of Immune Investment Strategies Across Amphibian Ontogeny," falls under NSF's Biological Sciences (CFDA 47.074) program, which supports basic research to strengthen the nation's scientific enterprise....
The National Science Foundation awarded a $413,329 Project Grant under the Biological Sciences (CFDA 47.074) program to the University of Colorado Boulder to support research integrating immune system and microbiome function during amphibian development from September 1, 2021 through August 31, 2024. The award will fund research examining how the immune system and microbiome interact and influence each other during amphibian growth and maturation. A subaward of $50,000 will support related...