Project Grant 2316468
- This Project Grant award from the National Science Foundation (NSF) Division of Emerging Frontiers, under the Biological Sciences program (CFDA 47.074), provides $388,992 to the University of Central Florida (UCF) to investigate the evolution of immune strategies across amphibian ontogeny. The key objectives are to: (1) use mathematical models and empirical data to predict when evolutionary history, pathogens, and environment favor T cell diversity within and among amphibian life stages; (2)...
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences Program (CFDA 47.074) is funding collaborative research led by Vanderbilt University to investigate how amphibian immune systems develop and adapt across life stages. The $274,765 project aims to: (1) use mathematical models and empirical data to understand how evolutionary history, pathogens, and environment influence T cell receptor diversity in frogs over ecological and evolutionary timescales; (2)...
- The National Science Foundation (NSF) Division of Emerging Frontiers awarded a $613,690 Project Grant to the University of Rochester to investigate the evolution of immune investment strategies across amphibian ontogeny. The project, titled "Collaborative Research: INTBIO: The Evolution of Immune Investment Strategies Across Amphibian Ontogeny," falls under NSF's Biological Sciences (CFDA 47.074) program, which supports basic research to strengthen the nation's scientific enterprise....
- The National Science Foundation awarded a $413,329 Project Grant under the Biological Sciences (CFDA 47.074) program to the University of Colorado Boulder to support research integrating immune system and microbiome function during amphibian development from September 1, 2021 through August 31, 2024. The award will fund research examining how the immune system and microbiome interact and influence each other during amphibian growth and maturation. A subaward of $50,000 will support related...
- The National Science Foundation (NSF) awarded a $494,261 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of North Carolina at Chapel Hill (UNC-CH) to conduct research on frog skin evolution and adaptations. The project aims to: 1) quantify how frog skin has evolved over the past 200 million years in response to abiotic and biotic factors, 2) experimentally test the ability of anuran skin to decouple respiration and water loss, and 3) incorporate...
- This $355,123 federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research to genetically modify the immune system of the African clawed frog (Xenopus tropicalis) to improve its resistance to the deadly chytrid fungus. The goal is to identify how altering the frog's major histocompatibility complex (MHC) genes affects its ability to fight off this pathogen and survive infection. The project includes a sub-award to the University...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $372,060 to the Research Foundation of the City University of New York (RFCUNY) - Brooklyn College will support research comparing the immune system structure, function, and memory in animal species with and without intact adaptive immune systems. The 3-year project aims to use single-cell RNA sequencing, immunization experiments, and pathogen exposure to better understand the evolutionary...
- This Project Grant award of $696,819.00 from the National Science Foundation's Biological Sciences (CFDA 47.074) program supports a collaborative research project to investigate innate immune responses in diverse microbial-feeding organisms across the evolutionary spectrum. The project brings together researchers from the University of Pittsburgh, University of Texas at Austin, and other institutions to study how sponges, choanoflagellates, and amoebae - which have high levels of microbial...
- This $240,000 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will fund a postdoctoral research fellowship to investigate the role of amphibian skin microbiomes in limiting the growth of deadly fungal pathogens. The research aims to explore the mechanisms by which certain skin microbes inhibit the fungal agents responsible for amphibian population declines, and to pilot the use of "antifungal probiotics" to protect...
- This Project Grant award of $335,268.00 was provided by the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program and awarded to the University of Texas at Austin on August 1, 2025 with an ultimate completion date of July 31, 2028. The project investigates a group of viral proteins that help viruses evade the immune systems of birds, reptiles, and insects. By studying how these viral proteins work across a wide range of animals, the research aims to uncover...
The National Science Foundation (NSF) awarded a $426,255 project grant under the Biological Sciences program (CFDA 47.074) to the University of Texas at Austin to investigate the evolution of immune system development across amphibian life stages. The key objectives are to: (1) use mathematical models and empirical data to predict how evolutionary history, pathogens, and environment influence T cell diversity within and among frog life stages; (2) quantify T cell receptor diversity across multiple frog species using molecular techniques; and (3) experimentally manipulate early-life diet and environment to assess developmental plasticity in frog T cell diversity and infection outcomes. This interdisciplinary research project aims to yield insights into the factors driving immune system maturation, plasticity, and diversity, while also training early-career scientists in immunology and frog biology. No subawards are planned under this grant, which has a performance period from Aug 15, 2023 to Jul 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $426.3k | 8/16/23 |