This $796,460 project grant from the National Science Foundation's Division of Integrative Organismal Systems and Biological Sciences program will fund research into the role of extracellular RNA in intercellular and interkingdom communication. The University of South Alabama will lead a collaborative effort between seven laboratories to advance understanding of how RNA secreted by host cells maintains healthy microbiomes in plants, insects, and humans. The researchers will test the hypothesis...
This four-year, $924,987 project grant from the National Science Foundation's Division of Integrative Organismal Systems and Directorate for Biological Sciences will fund research into the role of extracellular RNA (exRNA) in intercellular and interkingdom communication. Specifically, the collaborative project between seven laboratories will examine the hypothesis that RNA secreted by host cells plays a key role in maintaining microbiome and overall health through cell-to-cell communication...
This $805,832 project grant from the National Science Foundation's Division of Integrative Organismal Systems, under the Biological Sciences (CFDA 47.074) federal grant program, will fund research into the role of extracellular RNA in intercellular and interkingdom communication. A collaborative team of seven laboratories will investigate how RNA secreted by host cells influences microbiome health and composition in human gut, insect gut, and leaf surface models. Specifically, the researchers...
This Project Grant from the National Science Foundation's Division of Integrative Organismal Systems and Plant Genome Research Program and Plant Biotic Interactions Program, totaling $856,318, will fund research from March 1, 2023 to February 28, 2027. The grant supports a collaborative project between seven laboratories to further understanding of the role of extracellular RNA (exRNA) in intercellular and interkingdom communication. Specifically, the researchers aim to test the hypothesis...
This National Science Foundation project grant of $771,071 awarded on March 1, 2023 will fund research into the role of extracellular RNA (exRNA) in intercellular and interkingdom communication through February 28, 2027. The award is part of the Biological Sciences program under the CFDA number 47.074, which supports basic biological research to strengthen the Nation's scientific enterprise and increase knowledge of major problems. Specifically, a collaborative team of seven laboratories at...
The National Science Foundation (NSF) awarded a $919,999 Project Grant under the Biological Sciences program (CFDA 47.074) to the Regents of the University of California at Riverside. This 3-year grant, beginning September 1, 2023, supports research to investigate the evolution and functional role of small regulatory RNAs (sRNAs) in diverse bacterial lineages, particularly those living symbiotically within pest insect hosts. The project aims to determine how sRNA sequence divergence and...
This National Science Foundation (NSF) Project Grant, awarded under the Biological Sciences program (CFDA 47.074), provides $750,000 to Stanford University to develop new technologies for studying RNA, the essential molecules that carry genetic information and play crucial roles in cell functions. The key products and services to be delivered under this 3-year award include: Creating non-destructive methods to directly study RNA localization and interactions within living cells, achieving...
This $299,999 National Science Foundation project grant under the Biological Sciences program (CFDA 47.074) will support research exploring the RNA world and RNA-peptide world hypotheses using a novel dynamic combinatorial chemistry system at the University of Houston, a minority-serving institution. The two-year project beginning August 1, 2022 aims to advance understanding of the role of RNA and peptides in the origins of life. Investigators will employ a system using benzonuclease to cleave...
The National Science Foundation Division of Integrative Organismal Systems awarded Indiana University a $1.1 million Project Grant under the Biological Sciences federal grant program (CFDA 47.074) for the period April 1, 2022 through March 31, 2026. The grant funds collaborative research titled "Extracellular RNA Produced by Plants: What, Where, How, Who, and Why?" at Indiana University's Bloomington campus. The Biological Sciences program supports basic research to increase scientific...
The National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program has awarded $986,944.00 to William Marsh Rice University to develop a safe, programmable RNA-based system for transient protein production in bacteria. The "TOOLS4CELLS" project will engineer self-replicating RNA (sRNA) scaffolds derived from RNA bacteriophages to enable precise, short-term protein expression across a broad range of bacterial species without the risks of horizontal gene transfer...