This Project Grant from the National Science Foundation's Division of Integrative Organismal Systems and Plant Genome Research Program and Plant Biotic Interactions Program, totaling $856,318, will fund research from March 1, 2023 to February 28, 2027. The grant supports a collaborative project between seven laboratories to further understanding of the role of extracellular RNA (exRNA) in intercellular and interkingdom communication. Specifically, the researchers aim to test the hypothesis...
This four-year, $924,987 project grant from the National Science Foundation's Division of Integrative Organismal Systems and Directorate for Biological Sciences will fund research into the role of extracellular RNA (exRNA) in intercellular and interkingdom communication. Specifically, the collaborative project between seven laboratories will examine the hypothesis that RNA secreted by host cells plays a key role in maintaining microbiome and overall health through cell-to-cell communication...
This $796,460 project grant from the National Science Foundation's Division of Integrative Organismal Systems and Biological Sciences program will fund research into the role of extracellular RNA in intercellular and interkingdom communication. The University of South Alabama will lead a collaborative effort between seven laboratories to advance understanding of how RNA secreted by host cells maintains healthy microbiomes in plants, insects, and humans. The researchers will test the hypothesis...
This $805,832 project grant from the National Science Foundation's Division of Integrative Organismal Systems, under the Biological Sciences (CFDA 47.074) federal grant program, will fund research into the role of extracellular RNA in intercellular and interkingdom communication. A collaborative team of seven laboratories will investigate how RNA secreted by host cells influences microbiome health and composition in human gut, insect gut, and leaf surface models. Specifically, the researchers...
This four-year, $822,736 project grant from the National Science Foundation's Division of Integrative Organismal Systems and Biological Sciences program will fund research into the role of extracellular RNA in intercellular and interkingdom communication. Led by Clemson University, the collaborative project brings together seven laboratories to advance understanding of how RNA secreted by host cells maintains healthy microbiomes in plants, insects, and humans. The researchers will investigate...
This Project Grant award of $673,114 from the National Science Foundation's Biological Sciences Federal Grant Program (CFDA 47.074) supports a collaborative research project investigating the role of extracellular RNA (exRNA) produced by plants and its potential function in plant immune systems. The project aims to: 1) determine how plants secrete RNA and identify conserved exRNAs across diverse plant species, 2) assess whether post-transcriptional modifications are required for exRNA secretion,...
The National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) awarded a $810,001 project grant to The Trustees of the University of Pennsylvania to study the role of N6-methyladenosine (m6A) modifications in regulating plant gene expression and response to bacterial pathogens. The 4-year project aims to characterize the addition and removal of m6A on plant RNAs and investigate how these epitranscriptomic processes impact a plant's ability to recognize and respond to...
The National Science Foundation (NSF) awarded a $919,999 Project Grant under the Biological Sciences program (CFDA 47.074) to the Regents of the University of California at Riverside. This 3-year grant, beginning September 1, 2023, supports research to investigate the evolution and functional role of small regulatory RNAs (sRNAs) in diverse bacterial lineages, particularly those living symbiotically within pest insect hosts. The project aims to determine how sRNA sequence divergence and...
This $682,031 Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture (USDA NIFA) Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310) will fund research into exosomes as intercellular delivery vehicles in insects. Kansas State University will investigate the roles of exosomes in RNA interference (RNAi) responses and physiology in southern corn rootworm, using in vitro and in vivo models to identify components required for...
The National Science Foundation Division of Integrative Organismal Systems awarded Indiana University a $1.1 million Project Grant under the Biological Sciences federal grant program (CFDA 47.074) for the period April 1, 2022 through March 31, 2026. The grant funds collaborative research titled "Extracellular RNA Produced by Plants: What, Where, How, Who, and Why?" at Indiana University's Bloomington campus. The Biological Sciences program supports basic research to increase scientific...