Shotgun Metagenomic Sequencing

**The purpose of this amendment is to re-solicit as full and open competition and extend the closing date**

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice.  This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued.  Solicitation number 12505B23Q0248 is issued as a request for quote (RFQ).  The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2023-04 dated June 2, 2023.  This solicitation will be Full and Open Competition.  The associated NAICS code is 541714 (Research and Development in Biotechnology Except Nanobiotechnology), with a small business size standard of 1,000 employees.

This acquisition is for the following item as identified in the Line Items:

0001) Whole Genome Metagenomics deliverables: Quality report, FASTQ files, data QC, Azenta/GENEWIZ dynamic exploration of microbial taxonomy and abundance, cross-sample comparisons. Pan-metagenome data sanitation. Metagenomic assembly. BLAST assembled contigs for summary hits. NMDS,Krona, Abundance heatmap and Metastats. Description of Work: The USDA has a requirement to procure Whole Genome Metagenomics. Deliverables: Quality report, FASTQ files, data QC, Azenta/GENEWIZ dynamic exploration of microbial taxonomy and abundance, cross-sample comparisons. Pan-metagenome data sanitation. Metagenomic assembly. BLAST assembled contigs for summary hits. NMDS,Krona, Abundance heatmap and Metastats, located in Columbia, MO. The Contractor shall provide all items F.O.B. destination. The location of the Government site is 1053 S. Providence Rd, Columbia, MO 65203 and will also be identified in the contract.  The Government anticipates award of a Firm Fixed Price contract. Offerors responding to this announcement shall submit their quote in accordance with FAR 52.212-1 Instructions to Offerors—Commercial Products and Commercial Services and include a copy of 52.212-3 Offeror Representations-Commercial Products and Commercial Services.  Submission of quote shall include the following: (1) Technical and (2) Price.

All responses shall be submitted electronically to joel.maas@usda.gov

The basis for award is Lowest Price Technically Acceptable (LPTA).  LPTA means the best value is expected to result from selection of the technically acceptable quote with the lowest evaluated price.  Pursuant to FAR 52.212-2 Evaluation—Commercial Products and Commercial Services, the criteria for evaluation are: (1) Technical and (2) Price and must also have satisfactory Past Performance. The lowest priced quote will first be evaluated for technical acceptability in accordance with the minimum specifications identified.  If determined not technically acceptable, it will be removed from competition and the next lowest priced quote will be evaluated for technical acceptability.  This will continue until the lowest price quote is determined technically acceptable.  Once the lowest priced quote is determined technically acceptable, then a determination of responsibility will be completed.  If found responsible, evaluations will be closed and award will be made.

INSPECTON AND ACCEPTANCE TERMS:  Services will be inspected by Contracting Officer Representative (COR) and accepted at destination.  Delivery must be made by 60 days ARO.

To be eligible for an award, all contractors must be registered in the System for Award Management (SAM) at the time the quote is submitted.  A contractor can contact SAM by calling 1-866-606-8220 or www.sam.gov.  NO EXCEPTIONS. A SAM UEI number is required in order to register.  All invoices shall be submitted electronically.

Quotes must be received no later than 5:00 PM Eastern August 28, 2023.

Questions in regard to this combined synopsis/solicitation are due no later than 2:00 PM Eastern on August 25, 2023.  Answers to any questions received by that time will be posted as an amendment to this combined synopsis/solicitation.

DISCLAIMER: The official contract documents are located on the government webpage and the Government is not liable for information furnished by any other source. Amendments, if/when issued will be posted to Contract Opportunities for electronic downloading. This will normally be the only method of distributing amendments prior to closing; therefore, it is the offeror's responsibility to check the website periodically for any amendments to this solicitation. Websites are occasionally inaccessible, due to various reasons. The Government is not responsible for any loss of internet connectivity or for an offeror's inability to access the documents posted on the referenced web pages. The Government will not issue paper copies.

**The purpose of this amendment is to post a questions and answers page as well as an updated Statement of Work**

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice.  This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued.  Solicitation number 12505B23Q0248 is issued as a request for quote (RFQ).  The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2023-04 dated June 2, 2023.  This solicitation will be a Total Small Business set aside.  The associated NAICS code is 541714 (Research and Development in Biotechnology Except Nanobiotechnology), with a small business size standard of 1,000 employees.

This acquisition is for the following item as identified in the Line Items:

0001) Whole Genome Metagenomics deliverables: Quality report, FASTQ files, data QC, Azenta/GENEWIZ dynamic exploration of microbial taxonomy and abundance, cross-sample comparisons. Pan-metagenome data sanitation. Metagenomic assembly. BLAST assembled contigs for summary hits. NMDS,Krona, Abundance heatmap and Metastats. Description of Work: The USDA has a requirement to procure Whole Genome Metagenomics. Deliverables: Quality report, FASTQ files, data QC, Azenta/GENEWIZ dynamic exploration of microbial taxonomy and abundance, cross-sample comparisons. Pan-metagenome data sanitation. Metagenomic assembly. BLAST assembled contigs for summary hits. NMDS,Krona, Abundance heatmap and Metastats, located in Columbia, MO. The Contractor shall provide all items F.O.B. destination. The location of the Government site is 1053 S. Providence Rd, Columbia, MO 65203 and will also be identified in the contract.  The Government anticipates award of a Firm Fixed Price contract. Offerors responding to this announcement shall submit their quote in accordance with FAR 52.212-1 Instructions to Offerors—Commercial Products and Commercial Services and include a copy of 52.212-3 Offeror Representations-Commercial Products and Commercial Services.  Submission of quote shall include the following: (1) Technical and (2) Price.

All responses shall be submitted electronically to joel.maas@usda.gov

The basis for award is Lowest Price Technically Acceptable (LPTA).  LPTA means the best value is expected to result from selection of the technically acceptable quote with the lowest evaluated price.  Pursuant to FAR 52.212-2 Evaluation—Commercial Products and Commercial Services, the criteria for evaluation are: (1) Technical and (2) Price and must also have satisfactory Past Performance. The lowest priced quote will first be evaluated for technical acceptability in accordance with the minimum specifications identified.  If determined not technically acceptable, it will be removed from competition and the next lowest priced quote will be evaluated for technical acceptability.  This will continue until the lowest price quote is determined technically acceptable.  Once the lowest priced quote is determined technically acceptable, then a determination of responsibility will be completed.  If found responsible, evaluations will be closed and award will be made.

INSPECTON AND ACCEPTANCE TERMS:  Services will be inspected by Contracting Officer Representative (COR) and accepted at destination.  Delivery must be made by 60 days ARO.

To be eligible for an award, all contractors must be registered in the System for Award Management (SAM) at the time the quote is submitted.  A contractor can contact SAM by calling 1-866-606-8220 or www.sam.gov.  NO EXCEPTIONS. A SAM UEI number is required in order to register.  All invoices shall be submitted electronically.

Quotes must be received no later than 5:00 PM Eastern August 17, 2023.

Questions in regard to this combined synopsis/solicitation are due no later than 2:00 PM Eastern on August 14, 2023.  Answers to any questions received by that time will be posted as an amendment to this combined synopsis/solicitation.

DISCLAIMER: The official contract documents are located on the government webpage and the Government is not liable for information furnished by any other source. Amendments, if/when issued will be posted to Contract Opportunities for electronic downloading. This will normally be the only method of distributing amendments prior to closing; therefore, it is the offeror's responsibility to check the website periodically for any amendments to this solicitation. Websites are occasionally inaccessible, due to various reasons. The Government is not responsible for any loss of internet connectivity or for an offeror's inability to access the documents posted on the referenced web pages. The Government will not issue paper copies.

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice.  This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued.  Solicitation number 12505B23Q0248 is issued as a request for quote (RFQ).  The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2023-04 dated June 2, 2023.  This solicitation will be a Total Small Business set aside.  The associated NAICS code is 541714 (Research and Development in Biotechnology Except Nanobiotechnology), with a small business size standard of 1,000 employees.

This acquisition is for the following item as identified in the Line Items:

0001) Whole Genome Metagenomics deliverables: Quality report, FASTQ files, data QC, Azenta/GENEWIZ dynamic exploration of microbial taxonomy and abundance, cross-sample comparisons. Pan-metagenome data sanitation. Metagenomic assembly. BLAST assembled contigs for summary hits. NMDS,Krona, Abundance heatmap and Metastats. Description of Work: The USDA has a requirement to procure Whole Genome Metagenomics. Deliverables: Quality report, FASTQ files, data QC, Azenta/GENEWIZ dynamic exploration of microbial taxonomy and abundance, cross-sample comparisons. Pan-metagenome data sanitation. Metagenomic assembly. BLAST assembled contigs for summary hits. NMDS,Krona, Abundance heatmap and Metastats, located in Columbia, MO. The Contractor shall provide all items F.O.B. destination. The location of the Government site is 1053 S. Providence Rd, Columbia, MO 65203 and will also be identified in the contract.  The Government anticipates award of a Firm Fixed Price contract. Offerors responding to this announcement shall submit their quote in accordance with FAR 52.212-1 Instructions to Offerors—Commercial Products and Commercial Services and include a copy of 52.212-3 Offeror Representations-Commercial Products and Commercial Services.  Submission of quote shall include the following: (1) Technical and (2) Price.

All responses shall be submitted electronically to joel.maas@usda.gov

The basis for award is Lowest Price Technically Acceptable (LPTA).  LPTA means the best value is expected to result from selection of the technically acceptable quote with the lowest evaluated price.  Pursuant to FAR 52.212-2 Evaluation—Commercial Products and Commercial Services, the criteria for evaluation are: (1) Technical and (2) Price and must also have satisfactory Past Performance. The lowest priced quote will first be evaluated for technical acceptability in accordance with the minimum specifications identified.  If determined not technically acceptable, it will be removed from competition and the next lowest priced quote will be evaluated for technical acceptability.  This will continue until the lowest price quote is determined technically acceptable.  Once the lowest priced quote is determined technically acceptable, then a determination of responsibility will be completed.  If found responsible, evaluations will be closed and award will be made.

INSPECTON AND ACCEPTANCE TERMS:  Services will be inspected by Contracting Officer Representative (COR) and accepted at destination.  Delivery must be made by 60 days ARO.

To be eligible for an award, all contractors must be registered in the System for Award Management (SAM) at the time the quote is submitted.  A contractor can contact SAM by calling 1-866-606-8220 or www.sam.gov.  NO EXCEPTIONS. A SAM UEI number is required in order to register.  All invoices shall be submitted electronically.

Quotes must be received no later than 5:00 PM Eastern August 17, 2023.

Questions in regard to this combined synopsis/solicitation are due no later than 2:00 PM Eastern on August 14, 2023.  Answers to any questions received by that time will be posted as an amendment to this combined synopsis/solicitation.

DISCLAIMER: The official contract documents are located on the government webpage and the Government is not liable for information furnished by any other source. Amendments, if/when issued will be posted to Contract Opportunities for electronic downloading. This will normally be the only method of distributing amendments prior to closing; therefore, it is the offeror's responsibility to check the website periodically for any amendments to this solicitation. Websites are occasionally inaccessible, due to various reasons. The Government is not responsible for any loss of internet connectivity or for an offeror's inability to access the documents posted on the referenced web pages. The Government will not issue paper copies.