HGMD (Human Gene Mutation Database) MySQL software renewal

The National Institutes of Health, specifically the National Institute of Human Genome Research (NHGRI), is seeking to procure a renewal of HGMD (Human Gene Mutation Database) MySQL software through a firm-fixed-price purchase order. This software provides comprehensive data on human inherited disease mutations and is essential to maintain the functionality of the exome analysis pipeline used in the laboratory to identify disease-causing mutations in patient samples. The National Institutes of Health intends to sole source this contract to Qiagen, LLC, citing the software's unique integration into the existing laboratory pipeline and Qiagen's status as the only known responsible source capable of meeting the requirement. Small businesses, including 8(a) firms, service-disabled veteran-owned, HUBZone, small disadvantaged, veteran-owned, and women-owned small businesses, are invited to submit written capability statements demonstrating their ability to perform the requirement. The deadline for submission of capability statements is 11:00 a.m. EST on Monday, March 23, 2026, with submissions required via email to david.shen@nih.gov. Award is anticipated approximately five days after the notice date unless the Government determines another organization possesses the capability to meet the requirement.

This opportunity is not designated as a set-aside contract. Qiagen, LLC (UEI: W2GLKC92ZH73) is identified as the current and intended contractor, as the exclusive developer and distributor of HGMD software. The pre-solicitation notice does not disclose a specific contract value or budget range for this software renewal. While the notice specifies the goods are categorized under Software Publishers (NAICS 513210) and IT and Telecom Business Application Software with Perpetual License Software (PSC 7A21), no specific quantity of licenses, duration of the renewal period, or financial details are provided in the available documentation. Organizations interested in challenging the sole-source determination must act expeditiously, as the capability statement submission deadline of March 23, 2026, is only seven days from the notice posting date.