Clinical Long Read Genomics services for the NIAID Centralized Sequencing Program
Closed Solicitation Posted
- Solicitation number
- NOI-NIAID-25-2261604
- Agency
-
National Institute of Allergy and Infectious Diseases
National Institutes of Health, Department of Health and Human Services
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541380 Testing Laboratories and Services
- PSC
- Q301 Reference Laboratory Testing
- Place of performance
- Bethesda, Maryland 20892, United States
- Points of contact
Notice details come from SAM.gov. Updated .
About this opportunity
The National Institute of Allergy and Infectious Diseases (NIAID) is seeking clinical long read genomics services to support its Centralized Sequencing Program, which provides genetic testing and genomic evaluations for patients at the NIH Clinical Center. The procurement involves two types of genomic sequencing services: Targeted Long Read Sequencing requiring 12 reports and Long Read Symptom-Driven Analysis testing requiring 6 tests. The contractor must demonstrate expertise in genetics and genomics with strong communication and project management skills, and deliver comprehensive genomic analyses including Single Nucleotide Variants, Copy Number Variations, pseudogene clarification, methylation analysis, and repeat expansion analysis. This is a sole source procurement with NIAID planning to award to Children's Mercy Kansas City, which they believe is the only vendor capable of providing the required services. The solicitation was posted on August 15, 2025, with a response deadline of August 18, 2025, and NIAID plans to award the contract within 15 days of the notice publication.
This procurement does not utilize any set-aside designations and is structured as a sole source, firm-fixed price contract with Children's Mercy Kansas City as the intended awardee. The contract will have a 12-month performance period, though no specific award value or budget range is disclosed in the available documentation. The work will be performed in Bethesda, Maryland, supporting the Division of Intramural Research's mission of studying infectious diseases and providing clinically validated genomic results. While NIAID has identified Children's Mercy Kansas City as their preferred contractor, they are accepting capability statements from other potential vendors within 10 days of the notice publication. The genomic services are designed to contribute to understanding genetic disease etiology and have direct implications for patient care and disease mechanism discovery at the NIH Clinical Center.
Notice text
In support of clinical research, the NIAID Centralized Sequencing Program (CSP) is comprehensive program that obtains genetic testing, harmonizes phenotypic and genomic data, performs variant interpretation, and provides clinically validated results for patients enrolled in protocols at the NIH Clinical Center. The goal of the NIAID Centralized Sequencing Program is both to contribute to the understanding of underlying genetic etiology of disease and to address the clinical need for genomic evaluations.
The purpose of this acquisition is to support the mission of DIR to obtain genetic testing for the NIAID CSP. The objective is to purchase both symptom-driven long read sequencing analysis and targeted long read sequencing. The results of this testing will have direct implications for the care of NIH patients and for the discovery of disease mechanisms.
The scope of this effort includes the services and industry knowledge necessary to provide long read sequencing as specified in this SOW.
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