Auto Droplet Generator
Closed Special Notice Posted
- Solicitation number
- NIDDK07396
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 334516 Analytical Laboratory Instrument Manufacturing
- PSC
- 6640 Laboratory Equipment And Supplies
- Place of performance
- Bethesda, Maryland 20892, United States
- Points of contact
-
- Darin Mahkee mahkeed@nih.gov
Notice details come from SAM.gov. Updated .
About this opportunity
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the Department of Health and Human Services, issued a sole-source notice of intent on September 17, 2026 for an Auto Droplet Generator, with capability statements due by 10:00 a.m. EST on September 23, 2026. The notice identifies Bio-Rad Laboratories, Inc. (UEI: SSHPDYFGN7J9) as the sole-source recipient, though the Government retains discretion to compete the award if responses demonstrate another organization can meet the requirement.
The Diabetes Molecular Genetics Section uses the Auto Droplet Generator to automate droplet generation for droplet digital polymerase chain reaction workflows, reducing manual processing time and improving throughput and consistency in research involving pancreatic islets and islet organoids. The laboratory's current manual droplet generator, paired with a QX600 Droplet Digital PCR system, processes up to eight samples per cycle and requires time-consuming manual pipetting for full 96-well plate preparation.
Small businesses, including 8(a), service-disabled veteran-owned, HUBZone, small disadvantaged, veteran-owned, and women-owned small businesses, may submit written capability statements to mahkeed@nih.gov by the September 23 deadline demonstrating ability to perform the requirement. The Government anticipates award approximately ten days after the notice date. The purchase order will be Firm-Fixed-Price with all travel, labor, materials, and related charges included in the award price.
Notice text
The Diabetes Molecular Genetics Section of the Phoenix Epidemiology and Clinical Research Branch at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) studies pancreatic islet organoids derived from induced pluripotent stem cells to investigate molecular pathways associated with type 2 diabetes. The laboratory recently acquired a QX600 Droplet Digital Polymerase Chain Reaction system to generate cell type-specific gene expression data, perform methylation analysis for epigenomic studies, and estimate pancreatic islet composition using cell type-specific marker genes.
Currently, the laboratory uses a Manual Droplet Generator to prepare samples for droplet digital polymerase chain reaction analysis. Although the system can process up to eight samples at a time, preparation of a full 96-well plate is time-consuming and relies heavily on manual pipetting.
The Auto Droplet Generator shall automate droplet generation for droplet digital polymerase chain reaction workflows, reduce hands-on processing time, and improve throughput and consistency across experiments involving pancreatic islets and islet organoids.
Files
| File | Type | Posted |
|---|---|---|
| PCA-NIDDK-07396 NOI.docx | DOCX document |
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