ATTACHMENT C COSMOS Schedule.xlsx

This is a project schedule for the ARPA-H COSMOS (Comprehensive Organ System Modeling in Outer Space) Initiative spanning four fiscal years from FY27 through FY30 (calendar years 2027-2030). The schedule outlines a phased approach consisting of Phase I activities (Development & Testing, Pre-launch Integration and Hardware Validation) and Phase II activities (Launch Phase, Showcase, Model development/Scale Up/Integration Testing, and subsequent launches). The program is organized into 42 months divided into 15 program quarters, with key milestones including Design Lock for the Twin Study Morphological Platform System (MPS) and Commercial Space Platform (CSP) housing specifications, Hardware Validation Launch (HVL), four launch events (L1 through L4), and multiple data analysis periods. Critical governance events include Scientific Review Meetings (SRM) scheduled throughout the program. The schedule incorporates countdown timelines to launch events, with the initial launch occurring at Month 18-19 from program start, followed by additional launches at Months 24, 30, and 36, supporting the program's objective to study tissue aging acceleration in microgravity across multiple organ systems and age brackets to validate cost-effectiveness for autonomous drug screening in Low Earth Orbit.